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The impact of CCR8+ regulatory T cells on cytotoxic T cell function in human lung cancer
Regulatory T cells (Tregs) suppress the host immune response and maintain immune homeostasis. Tregs also promote cancer progression and are involved in resistance to immune checkpoint inhibitor treatments. Recent studies identified selective CCR8 expression on tumor-infiltrating Tregs; CCR8+ Tregs h...
Autores principales: | Haruna, Miya, Ueyama, Azumi, Yamamoto, Yoko, Hirata, Michinari, Goto, Kumiko, Yoshida, Hiroshi, Higuchi, Naoko, Yoshida, Tetsuya, Kidani, Yujiro, Nakamura, Yamami, Nagira, Morio, Kawashima, Atsunari, Iwahori, Kota, Shintani, Yasushi, Ohkura, Naganari, Wada, Hisashi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8967908/ https://www.ncbi.nlm.nih.gov/pubmed/35354899 http://dx.doi.org/10.1038/s41598-022-09458-5 |
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