Cargando…

The Value of Shear Wave Elastography in the Diagnosis of Breast Cancer Axillary Lymph Node Metastasis and Its Correlation With Molecular Classification of Breast Masses

OBJECTIVE: To explore the diagnostic value of shear wave elastography examination (SWE) on axillary node metastasis (ANM) in breast cancer, this study aimed to evaluate the correlation between the SWE features and different molecular types of breast cancer, and to check the elastic modulus differenc...

Descripción completa

Detalles Bibliográficos
Autores principales: Luo, Changyun, Lu, Li, Zhang, Weifu, Li, Xiangqi, Zhou, Ping, Ran, Zhangshen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8968036/
https://www.ncbi.nlm.nih.gov/pubmed/35372023
http://dx.doi.org/10.3389/fonc.2022.846568
_version_ 1784678960453386240
author Luo, Changyun
Lu, Li
Zhang, Weifu
Li, Xiangqi
Zhou, Ping
Ran, Zhangshen
author_facet Luo, Changyun
Lu, Li
Zhang, Weifu
Li, Xiangqi
Zhou, Ping
Ran, Zhangshen
author_sort Luo, Changyun
collection PubMed
description OBJECTIVE: To explore the diagnostic value of shear wave elastography examination (SWE) on axillary node metastasis (ANM) in breast cancer, this study aimed to evaluate the correlation between the SWE features and different molecular types of breast cancer, and to check the elastic modulus differences among the molecular types. METHODS: Breast cancer patients from November 2020 to December 2021 were subjected to both conventional ultrasonic examination (CUE) and SWE before ultrasound-guided percutaneous biopsy or axillary lymph node dissection (ALND). We used the pathological results as the gold standard to draw the receiver operating characteristic (ROC) curve. RESULTS: SWE outperforms CUE, but their conjunctive use is the best option. No significant correlation was found between the elastic modulus values and the molecular types of breast cancer. CONCLUSION: SWE can be used as an routine auxiliary method of CUE for ANM.
format Online
Article
Text
id pubmed-8968036
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-89680362022-04-01 The Value of Shear Wave Elastography in the Diagnosis of Breast Cancer Axillary Lymph Node Metastasis and Its Correlation With Molecular Classification of Breast Masses Luo, Changyun Lu, Li Zhang, Weifu Li, Xiangqi Zhou, Ping Ran, Zhangshen Front Oncol Oncology OBJECTIVE: To explore the diagnostic value of shear wave elastography examination (SWE) on axillary node metastasis (ANM) in breast cancer, this study aimed to evaluate the correlation between the SWE features and different molecular types of breast cancer, and to check the elastic modulus differences among the molecular types. METHODS: Breast cancer patients from November 2020 to December 2021 were subjected to both conventional ultrasonic examination (CUE) and SWE before ultrasound-guided percutaneous biopsy or axillary lymph node dissection (ALND). We used the pathological results as the gold standard to draw the receiver operating characteristic (ROC) curve. RESULTS: SWE outperforms CUE, but their conjunctive use is the best option. No significant correlation was found between the elastic modulus values and the molecular types of breast cancer. CONCLUSION: SWE can be used as an routine auxiliary method of CUE for ANM. Frontiers Media S.A. 2022-03-17 /pmc/articles/PMC8968036/ /pubmed/35372023 http://dx.doi.org/10.3389/fonc.2022.846568 Text en Copyright © 2022 Luo, Lu, Zhang, Li, Zhou and Ran https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Luo, Changyun
Lu, Li
Zhang, Weifu
Li, Xiangqi
Zhou, Ping
Ran, Zhangshen
The Value of Shear Wave Elastography in the Diagnosis of Breast Cancer Axillary Lymph Node Metastasis and Its Correlation With Molecular Classification of Breast Masses
title The Value of Shear Wave Elastography in the Diagnosis of Breast Cancer Axillary Lymph Node Metastasis and Its Correlation With Molecular Classification of Breast Masses
title_full The Value of Shear Wave Elastography in the Diagnosis of Breast Cancer Axillary Lymph Node Metastasis and Its Correlation With Molecular Classification of Breast Masses
title_fullStr The Value of Shear Wave Elastography in the Diagnosis of Breast Cancer Axillary Lymph Node Metastasis and Its Correlation With Molecular Classification of Breast Masses
title_full_unstemmed The Value of Shear Wave Elastography in the Diagnosis of Breast Cancer Axillary Lymph Node Metastasis and Its Correlation With Molecular Classification of Breast Masses
title_short The Value of Shear Wave Elastography in the Diagnosis of Breast Cancer Axillary Lymph Node Metastasis and Its Correlation With Molecular Classification of Breast Masses
title_sort value of shear wave elastography in the diagnosis of breast cancer axillary lymph node metastasis and its correlation with molecular classification of breast masses
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8968036/
https://www.ncbi.nlm.nih.gov/pubmed/35372023
http://dx.doi.org/10.3389/fonc.2022.846568
work_keys_str_mv AT luochangyun thevalueofshearwaveelastographyinthediagnosisofbreastcanceraxillarylymphnodemetastasisanditscorrelationwithmolecularclassificationofbreastmasses
AT luli thevalueofshearwaveelastographyinthediagnosisofbreastcanceraxillarylymphnodemetastasisanditscorrelationwithmolecularclassificationofbreastmasses
AT zhangweifu thevalueofshearwaveelastographyinthediagnosisofbreastcanceraxillarylymphnodemetastasisanditscorrelationwithmolecularclassificationofbreastmasses
AT lixiangqi thevalueofshearwaveelastographyinthediagnosisofbreastcanceraxillarylymphnodemetastasisanditscorrelationwithmolecularclassificationofbreastmasses
AT zhouping thevalueofshearwaveelastographyinthediagnosisofbreastcanceraxillarylymphnodemetastasisanditscorrelationwithmolecularclassificationofbreastmasses
AT ranzhangshen thevalueofshearwaveelastographyinthediagnosisofbreastcanceraxillarylymphnodemetastasisanditscorrelationwithmolecularclassificationofbreastmasses
AT luochangyun valueofshearwaveelastographyinthediagnosisofbreastcanceraxillarylymphnodemetastasisanditscorrelationwithmolecularclassificationofbreastmasses
AT luli valueofshearwaveelastographyinthediagnosisofbreastcanceraxillarylymphnodemetastasisanditscorrelationwithmolecularclassificationofbreastmasses
AT zhangweifu valueofshearwaveelastographyinthediagnosisofbreastcanceraxillarylymphnodemetastasisanditscorrelationwithmolecularclassificationofbreastmasses
AT lixiangqi valueofshearwaveelastographyinthediagnosisofbreastcanceraxillarylymphnodemetastasisanditscorrelationwithmolecularclassificationofbreastmasses
AT zhouping valueofshearwaveelastographyinthediagnosisofbreastcanceraxillarylymphnodemetastasisanditscorrelationwithmolecularclassificationofbreastmasses
AT ranzhangshen valueofshearwaveelastographyinthediagnosisofbreastcanceraxillarylymphnodemetastasisanditscorrelationwithmolecularclassificationofbreastmasses