Atypical Expression of Smooth Muscle Markers and Co-activators and Their Regulation in Rheumatic Aortic and Calcified Bicuspid Valves

OBJECTIVE: We have previously reported that human calcified aortic cusps have abundant expression of smooth muscle (SM) markers and co-activators. We hypothesised that cells in bicuspid aortic valve (BAV) cusps and those affected by rheumatic heart valve (RHV) disease may follow a similar phenotypic...

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Detalles Bibliográficos
Autores principales: Latif, Najma, Sarathchandra, Padmini, McCormack, Ann, Yacoub, Magdi H., Chester, Adrian H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8968087/
https://www.ncbi.nlm.nih.gov/pubmed/35369286
http://dx.doi.org/10.3389/fcvm.2022.793666

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8968087/
https://www.ncbi.nlm.nih.gov/pubmed/35369286
http://dx.doi.org/10.3389/fcvm.2022.793666

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