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Atypical Expression of Smooth Muscle Markers and Co-activators and Their Regulation in Rheumatic Aortic and Calcified Bicuspid Valves
OBJECTIVE: We have previously reported that human calcified aortic cusps have abundant expression of smooth muscle (SM) markers and co-activators. We hypothesised that cells in bicuspid aortic valve (BAV) cusps and those affected by rheumatic heart valve (RHV) disease may follow a similar phenotypic...
Autores principales: | Latif, Najma, Sarathchandra, Padmini, McCormack, Ann, Yacoub, Magdi H., Chester, Adrian H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8968087/ https://www.ncbi.nlm.nih.gov/pubmed/35369286 http://dx.doi.org/10.3389/fcvm.2022.793666 |
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