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The Prevalence and Risk Factors for Severe Maternal Morbidities: A Systematic Review and Meta-Analysis

INTRODUCTION: Maternal mortality and severe maternal morbidity remain major public health problems globally. Understanding their risk factors may result in better treatment solutions and preventive measures for maternal health. This review aims to identify the prevalence and risk factors of severe m...

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Autores principales: Nik Hazlina, Nik Hussain, Norhayati, Mohd Noor, Shaiful Bahari, Ismail, Mohamed Kamil, Halilul Rahman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8968119/
https://www.ncbi.nlm.nih.gov/pubmed/35372381
http://dx.doi.org/10.3389/fmed.2022.861028
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author Nik Hazlina, Nik Hussain
Norhayati, Mohd Noor
Shaiful Bahari, Ismail
Mohamed Kamil, Halilul Rahman
author_facet Nik Hazlina, Nik Hussain
Norhayati, Mohd Noor
Shaiful Bahari, Ismail
Mohamed Kamil, Halilul Rahman
author_sort Nik Hazlina, Nik Hussain
collection PubMed
description INTRODUCTION: Maternal mortality and severe maternal morbidity remain major public health problems globally. Understanding their risk factors may result in better treatment solutions and preventive measures for maternal health. This review aims to identify the prevalence and risk factors of severe maternal morbidity (SMM) and maternal near miss (MNM). METHODS: A systematic review and meta-analysis was conducted to assess the prevalence and risk factors of SMM and MNM. The study adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. A systematic search was performed in the MEDLINE (PubMed), CINAHL (EBSCOhost), and Science Direct databases for articles published between 2011 and 2020. RESULTS: Twenty-four of the 44 studies included were assessed as being of good quality and having a low risk of bias. The prevalence of SMM and MNM was 2.45% (95% CI: 2.03, 2.88) and 1.68% (95% CI: 1.42, 1.95), respectively. The risk factors for SMM included history of cesarean section (OR [95% CI]: 1.63 [1.43, 1.87]), young maternal age (OR [95% CI]: 0.71 [0.60, 0.83]), singleton pregnancy (OR [95% CI]: 0.42 [0.32, 0.55]), vaginal delivery (OR [95% CI]: 0.11 [0.02, 0.47]), coexisting medical conditions (OR [95% CI]: 1.51 [1.28, 1.78]), and preterm gestation (OR [95% CI]: 0.14 [0.08, 0.23]). The sole risk factor for MNM was a history of cesarean section (OR [95% CI]: 2.68 [1.41, 5.10]). CONCLUSIONS: Maternal age, coexisting medical conditions, history of abortion and cesarean delivery, gestational age, parity, and mode of delivery are associated with SMM and MNM. This helps us better understand the risk factors and their strength of association with SMM and MNM. Thus, initiatives such as educational programs, campaigns, and early detection of risk factors are recommended. Proper follow-up is important to monitor the progression of maternal health during the antenatal and postnatal periods. SYSTEMATIC REVIEW REGISTRATION: https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021226137, identifier: CRD42021226137.
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spelling pubmed-89681192022-04-01 The Prevalence and Risk Factors for Severe Maternal Morbidities: A Systematic Review and Meta-Analysis Nik Hazlina, Nik Hussain Norhayati, Mohd Noor Shaiful Bahari, Ismail Mohamed Kamil, Halilul Rahman Front Med (Lausanne) Medicine INTRODUCTION: Maternal mortality and severe maternal morbidity remain major public health problems globally. Understanding their risk factors may result in better treatment solutions and preventive measures for maternal health. This review aims to identify the prevalence and risk factors of severe maternal morbidity (SMM) and maternal near miss (MNM). METHODS: A systematic review and meta-analysis was conducted to assess the prevalence and risk factors of SMM and MNM. The study adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. A systematic search was performed in the MEDLINE (PubMed), CINAHL (EBSCOhost), and Science Direct databases for articles published between 2011 and 2020. RESULTS: Twenty-four of the 44 studies included were assessed as being of good quality and having a low risk of bias. The prevalence of SMM and MNM was 2.45% (95% CI: 2.03, 2.88) and 1.68% (95% CI: 1.42, 1.95), respectively. The risk factors for SMM included history of cesarean section (OR [95% CI]: 1.63 [1.43, 1.87]), young maternal age (OR [95% CI]: 0.71 [0.60, 0.83]), singleton pregnancy (OR [95% CI]: 0.42 [0.32, 0.55]), vaginal delivery (OR [95% CI]: 0.11 [0.02, 0.47]), coexisting medical conditions (OR [95% CI]: 1.51 [1.28, 1.78]), and preterm gestation (OR [95% CI]: 0.14 [0.08, 0.23]). The sole risk factor for MNM was a history of cesarean section (OR [95% CI]: 2.68 [1.41, 5.10]). CONCLUSIONS: Maternal age, coexisting medical conditions, history of abortion and cesarean delivery, gestational age, parity, and mode of delivery are associated with SMM and MNM. This helps us better understand the risk factors and their strength of association with SMM and MNM. Thus, initiatives such as educational programs, campaigns, and early detection of risk factors are recommended. Proper follow-up is important to monitor the progression of maternal health during the antenatal and postnatal periods. SYSTEMATIC REVIEW REGISTRATION: https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021226137, identifier: CRD42021226137. Frontiers Media S.A. 2022-03-17 /pmc/articles/PMC8968119/ /pubmed/35372381 http://dx.doi.org/10.3389/fmed.2022.861028 Text en Copyright © 2022 Nik Hazlina, Norhayati, Shaiful Bahari and Mohamed Kamil. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Medicine
Nik Hazlina, Nik Hussain
Norhayati, Mohd Noor
Shaiful Bahari, Ismail
Mohamed Kamil, Halilul Rahman
The Prevalence and Risk Factors for Severe Maternal Morbidities: A Systematic Review and Meta-Analysis
title The Prevalence and Risk Factors for Severe Maternal Morbidities: A Systematic Review and Meta-Analysis
title_full The Prevalence and Risk Factors for Severe Maternal Morbidities: A Systematic Review and Meta-Analysis
title_fullStr The Prevalence and Risk Factors for Severe Maternal Morbidities: A Systematic Review and Meta-Analysis
title_full_unstemmed The Prevalence and Risk Factors for Severe Maternal Morbidities: A Systematic Review and Meta-Analysis
title_short The Prevalence and Risk Factors for Severe Maternal Morbidities: A Systematic Review and Meta-Analysis
title_sort prevalence and risk factors for severe maternal morbidities: a systematic review and meta-analysis
topic Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8968119/
https://www.ncbi.nlm.nih.gov/pubmed/35372381
http://dx.doi.org/10.3389/fmed.2022.861028
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