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Undernourished patients do not have increased risk of severe COVID-19 outcomes

BACKGROUND: Undernutrition has been previously identified as a deleterious factor in acute infections. In covid-19 infection, obesity is a risk-factor of severe evolution, but initial undernutrition has not been evaluated yet. METHODS: We retrospectively analyzed correlation between nutritional stat...

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Autores principales: Fneich, Ahmad, Poinsot, Pierre, Elias, Christelle, Restier, Lioara, Vanhems, Philippe, Wallet, Florent, Caussy, Cyrielle, Duclos, Antoine, Peretti, Noël
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Ltd on behalf of European Society for Clinical Nutrition and Metabolism. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8968129/
https://www.ncbi.nlm.nih.gov/pubmed/35378830
http://dx.doi.org/10.1016/j.nutos.2022.03.002
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author Fneich, Ahmad
Poinsot, Pierre
Elias, Christelle
Restier, Lioara
Vanhems, Philippe
Wallet, Florent
Caussy, Cyrielle
Duclos, Antoine
Peretti, Noël
author_facet Fneich, Ahmad
Poinsot, Pierre
Elias, Christelle
Restier, Lioara
Vanhems, Philippe
Wallet, Florent
Caussy, Cyrielle
Duclos, Antoine
Peretti, Noël
author_sort Fneich, Ahmad
collection PubMed
description BACKGROUND: Undernutrition has been previously identified as a deleterious factor in acute infections. In covid-19 infection, obesity is a risk-factor of severe evolution, but initial undernutrition has not been evaluated yet. METHODS: We retrospectively analyzed correlation between nutritional status at admission and severe outcomes (intensive care unit admission, invasive mechanical ventilation requirement and death) of patients hospitalized for confirmed covid-19 infection. RESULTS: Risk of intensive care unit admission and invasive mechanical ventilation requirement was not significantly different between undernutrition and normoweight sub-groups, but increased in excessive weight sub-group (ODDR (IC 95%) 1.048 (1.011-1.086), p = 0.011). Risk of death was the same in all sub-groups. CONCLUSION: Undernutrition didn't appear as a factor of severe outcomes in covid-19 infection.
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spelling pubmed-89681292022-03-31 Undernourished patients do not have increased risk of severe COVID-19 outcomes Fneich, Ahmad Poinsot, Pierre Elias, Christelle Restier, Lioara Vanhems, Philippe Wallet, Florent Caussy, Cyrielle Duclos, Antoine Peretti, Noël Clin Nutr Open Sci Short Communication BACKGROUND: Undernutrition has been previously identified as a deleterious factor in acute infections. In covid-19 infection, obesity is a risk-factor of severe evolution, but initial undernutrition has not been evaluated yet. METHODS: We retrospectively analyzed correlation between nutritional status at admission and severe outcomes (intensive care unit admission, invasive mechanical ventilation requirement and death) of patients hospitalized for confirmed covid-19 infection. RESULTS: Risk of intensive care unit admission and invasive mechanical ventilation requirement was not significantly different between undernutrition and normoweight sub-groups, but increased in excessive weight sub-group (ODDR (IC 95%) 1.048 (1.011-1.086), p = 0.011). Risk of death was the same in all sub-groups. CONCLUSION: Undernutrition didn't appear as a factor of severe outcomes in covid-19 infection. Published by Elsevier Ltd on behalf of European Society for Clinical Nutrition and Metabolism. 2022-08 2022-03-31 /pmc/articles/PMC8968129/ /pubmed/35378830 http://dx.doi.org/10.1016/j.nutos.2022.03.002 Text en © 2022 The Authors Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Short Communication
Fneich, Ahmad
Poinsot, Pierre
Elias, Christelle
Restier, Lioara
Vanhems, Philippe
Wallet, Florent
Caussy, Cyrielle
Duclos, Antoine
Peretti, Noël
Undernourished patients do not have increased risk of severe COVID-19 outcomes
title Undernourished patients do not have increased risk of severe COVID-19 outcomes
title_full Undernourished patients do not have increased risk of severe COVID-19 outcomes
title_fullStr Undernourished patients do not have increased risk of severe COVID-19 outcomes
title_full_unstemmed Undernourished patients do not have increased risk of severe COVID-19 outcomes
title_short Undernourished patients do not have increased risk of severe COVID-19 outcomes
title_sort undernourished patients do not have increased risk of severe covid-19 outcomes
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8968129/
https://www.ncbi.nlm.nih.gov/pubmed/35378830
http://dx.doi.org/10.1016/j.nutos.2022.03.002
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