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NTRK Fusion in Non-Small Cell Lung Cancer: Diagnosis, Therapy, and TRK Inhibitor Resistance

Neurotrophic tropomyosin receptor kinase (NTRK) gene fusion has been identified as an oncogenic driver of various solid tumors, and it is rare in non-smalll cell lung cancer (NSCLC) with a frequency of approximately less than 1%. Next-generation sequencing (NGS) is of priority for detecting NTRK fus...

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Detalles Bibliográficos
Autores principales: Liu, Fangfang, Wei, Yuxuan, Zhang, Huan, Jiang, Jizong, Zhang, Peng, Chu, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8968138/
https://www.ncbi.nlm.nih.gov/pubmed/35372074
http://dx.doi.org/10.3389/fonc.2022.864666