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Druggability of Voltage-Gated Sodium Channels—Exploring Old and New Drug Receptor Sites
Voltage-gated ion channels are important drug targets because they play crucial physiological roles in both excitable and non-excitable cells. About 15% of clinical drugs used for treating human diseases target ion channels. However, most of these drugs do not provide sufficient specificity to a sin...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8968173/ https://www.ncbi.nlm.nih.gov/pubmed/35370700 http://dx.doi.org/10.3389/fphar.2022.858348 |