YY1-induced lncRNA XIST inhibits cartilage differentiation of BMSCs by binding with TAF15 to stabilizing FUT1 expression

INTRODUCTION: The functional roles and mechanism of the XIST in osteoarthritis and the chondrogenic differentiation of BMSCs were clarified. METHODS: The expression levels of XIST, TAF15, FUT1 and YY1 were detected through quantitative RT-PCR. The protein expression of Sox9, ACAN, COL2A1 and FUT1 we...

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Detalles Bibliográficos
Autores principales: He, Jian-Ying, Cheng, Min, Ye, Jia-Lian, Peng, Chuan-Hua, Chen, Jian, Luo, Bin, Zhang, Xian-Yu, Fu, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society for Regenerative Medicine 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8968204/
https://www.ncbi.nlm.nih.gov/pubmed/35402663
http://dx.doi.org/10.1016/j.reth.2022.02.002

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