ETS-related gene (ERG) undermines genome stability in mouse prostate progenitors via Gsk3β dependent Nkx3.1 degradation

21q22.2–3 deletion is the most common copy number alteration in prostate cancer (PCa). The genomic rearrangement results in the androgen-dependent de novo expression of ETS-related gene (ERG) in prostate cancer cells, a condition promoting tumor progression to advanced stages of the disease. Interes...

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Detalles Bibliográficos
Autores principales: Lorenzoni, Marco, De Felice, Dario, Beccaceci, Giulia, Di Donato, Giorgia, Foletto, Veronica, Genovesi, Sacha, Bertossi, Arianna, Cambuli, Francesco, Lorenzin, Francesca, Savino, Aurora, Avalle, Lidia, Cimadamore, Alessia, Montironi, Rodolfo, Weber, Veronica, Carbone, Francesco Giuseppe, Barbareschi, Mattia, Demichelis, Francesca, Romanel, Alessandro, Poli, Valeria, Del Sal, Giannino, Julio, Marianna Kruithof-de, Gaspari, Marco, Alaimo, Alessandro, Lunardi, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ireland 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8968219/
https://www.ncbi.nlm.nih.gov/pubmed/35259458
http://dx.doi.org/10.1016/j.canlet.2022.215612

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