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Prostaglandin EP4 Selective Agonist AKDS001 Enhances New Bone Formation by Minimodeling in a Rat Heterotopic Xenograft Model of Human Bone

To enhance bone regeneration, the use of bone morphogenetic protein (BMP)-2 is an attractive option. Unfortunately, the dose-dependent side effects prevent its widespread use. Therefore, a novel osteogenic agent using a different mechanism of action than BMP-2 is highly desirable. Previous reports d...

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Detalles Bibliográficos
Autores principales:	Ukon, Yuichiro, Nishida, Masahiro, Yamamori, Natsumi, Takeyama, Kazuhiro, Sakamoto, Kazuhito, Takenaka, Shota, Makino, Takahiro, Fujimori, Takahito, Sakai, Yusuke, Kanie, Yuya, Kodama, Joe, Bal, Zeynep, Tateiwa, Daisuke, Nakagawa, Shinichi, Hirai, Hiromasa, Okada, Seiji, Kaito, Takashi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8968459/ https://www.ncbi.nlm.nih.gov/pubmed/35372320 http://dx.doi.org/10.3389/fbioe.2022.845716

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