Dll1 Can Function as a Ligand of Notch1 and Notch2 in the Thymic Epithelium

T-cell development in the thymus is dependent on Notch signaling induced by the interaction of Notch1, present on immigrant cells, with a Notch ligand, delta-like (Dll) 4, on the thymic epithelial cells. Phylogenetic analysis characterizing the properties of the Dll4 molecule suggests that Dll4 emer...

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Detalles Bibliográficos
Autores principales: Hirano, Ken-ichi, Hosokawa, Hiroyuki, Yahata, Takashi, Ando, Kiyoshi, Tanaka, Masayuki, Imai, Jin, Yazawa, Masaki, Ohtsuka, Masato, Negishi, Naoko, Habu, Sonoko, Sato, Takehito, Hozumi, Katsuto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8968733/
https://www.ncbi.nlm.nih.gov/pubmed/35371023
http://dx.doi.org/10.3389/fimmu.2022.852427

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