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Otic Organoids Containing Spiral Ganglion Neuron-like Cells Derived from Human-induced Pluripotent Stem Cells as a Model of Drug-induced Neuropathy

The spiral ganglion of the cochlea is essential for hearing and contains primary bipolar neurons that relay action potentials generated by mechanosensory hair cells. Injury to spiral ganglion neurons (SGNs) causes permanent hearing loss because these cells have limited regenerative capacity. Establi...

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Detalles Bibliográficos
Autores principales:	Kurihara, Sho, Fujioka, Masato, Hirabayashi, Motoki, Yoshida, Tomohiko, Hosoya, Makoto, Nagase, Masashi, Kato, Fusao, Ogawa, Kaoru, Okano, Hideyuki, Kojima, Hiromi, Okano, Hirotaka James
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Cell-Based Drug Development, Screening, and Toxicology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8968745/ https://www.ncbi.nlm.nih.gov/pubmed/35356976 http://dx.doi.org/10.1093/stcltm/szab023

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