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IFNγ enhances ferroptosis by increasing JAK-STAT pathway activation to suppress SLCA711 expression in adrenocortical carcinoma

Adrenocortical carcinoma (ACC) is a rare type of tumor with a poor prognosis. Ferroptosis is a relatively novel form of programmed cell death driven by iron-dependent lipid peroxidation accumulation. Recent evidence suggests that IFNγ facilitates erastin-induced ferroptosis, which contributed to ant...

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Detalles Bibliográficos
Autores principales: Yu, Xinbo, Zhu, Dandan, Luo, Bixian, Kou, Wei, Cheng, Yuling, Zhu, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8968764/
https://www.ncbi.nlm.nih.gov/pubmed/35322867
http://dx.doi.org/10.3892/or.2022.8308