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Epithelial cell adhesion molecule-targeting designed ankyrin repeat protein-toxin fusion Ec1-LoPE exhibits potent cytotoxic action in prostate cancer cells

Targeted anticancer therapeutics offer the advantage of reducing cytotoxic side effects to normal cells by directing the cytotoxic payload selectively to cancer cells. Designed ankyrin repeat proteins (DARPins) are promising non-immunoglobulin-based scaffold proteins for payload delivery to cancer-a...

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Detalles Bibliográficos
Autores principales:	Xu, Tianqi, Liu, Yongsheng, Schulga, Alexey, Konovalova, Elena, Deyev, Sergey M., Tolmachev, Vladimir, Vorobyeva, Anzhelika
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8968790/ https://www.ncbi.nlm.nih.gov/pubmed/35315504 http://dx.doi.org/10.3892/or.2022.8305

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