Cargando…

Application of 3D Hepatic Plate-Like Liver Model for Statin-Induced Hepatotoxicity Evaluation

Background: Drug-induced liver injury is one of the main reasons of withdrawals of drugs in postmarketing stages. However, an experimental model(s) which can accurately recapitulates liver functions and reflects the level of drug hepatotoxicity is lack. In this study, we assessed drug hepatotoxicity...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Jiecheng, Pan, Daogang, Liao, Wei, Jia, Zhidong, Pan, Mingxin, Weng, Jun, Han, Xu, Li, Shao, Li, Yang, Liang, Kangyan, Zhou, Shuqin, Peng, Qing, Gao, Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8968918/ https://www.ncbi.nlm.nih.gov/pubmed/35372314 http://dx.doi.org/10.3389/fbioe.2022.826093

Ejemplares similares

High-throughput three-dimensional spheroid tumor model using a novel stamp-like tool
por: Liao, Wei, et al.
Publicado: (2019)

Pre-treatment With PLGA/Silibinin Nanoparticles Mitigates Dacarbazine-Induced Hepatotoxicity
por: Durymanov, Mikhail, et al.
Publicado: (2020)

Biomechanical effects of different numbers and locations of screw-in clavicle hook plates
por: Wang, Cheng-Chi, et al.
Publicado: (2022)

Engineered exosomes derived from miR-132-overexpresssing adipose stem cells promoted diabetic wound healing and skin reconstruction
por: Ge, Lifeng, et al.
Publicado: (2023)

Therapeutic Potential of CUDC-907 (Fimepinostat) for Hepatocarcinoma Treatment Revealed by Tumor Spheroids-Based Drug Screening
por: Liao, Wei, et al.
Publicado: (2021)

Evaluating the biomechanical performance of Ti6Al4V volar plates in patients with distal radius fractures
por: Li, Hua, et al.
Publicado: (2023)

Analysis of Mechanical Properties and Permeability of Trabecular-Like Porous Scaffold by Additive Manufacturing
por: Chao, Long, et al.
Publicado: (2021)

Combined Medial Plate and Intramedullary Nailing for the Fixation of Extra-Articular Proximal Tibial Fractures: a Biomechanics Study
por: Lu, Yao, et al.
Publicado: (2022)

Tri-element nanozyme PtCuSe as an ingenious cascade catalytic machine for the amelioration of Parkinson’s disease-like symptoms
por: Xu, Hongdang, et al.
Publicado: (2023)

Efficacy comparison of Kirschner-wire tension band combined with patellar cerclage and anchor-loop plate in treatment of inferior patellar pole fracture
por: Du, Bing, et al.
Publicado: (2022)

The Study of Biomechanics and Clinical Anatomy on a Novel Plate Designed for Posterolateral Tibial Plateau Fractures via Anterolateral Approach
por: Ren, Weizhi, et al.
Publicado: (2022)

De novo Design of G Protein-Coupled Receptor 40 Peptide Agonists for Type 2 Diabetes Mellitus Based on Artificial Intelligence and Site-Directed Mutagenesis
por: Chen, Xu, et al.
Publicado: (2021)

Influence of tension-band plates on the mechanical loading of the femoral growth plate during guided growth due to coronal plane deformities
por: Hucke, Lucie, et al.
Publicado: (2023)

In vitro to in vivo acetaminophen hepatotoxicity extrapolation using classical schemes, pharmacodynamic models and a multiscale spatial-temporal liver twin
por: Dichamp, Jules, et al.
Publicado: (2023)

Injectable hydrogel loaded with bilayer microspheres to inhibit angiogenesis and promote cartilage regeneration for repairing growth plate injury
por: Qiang, Lei, et al.
Publicado: (2023)

Enlightenment of Growth Plate Regeneration Based on Cartilage Repair Theory: A Review
por: Wang, Xianggang, et al.
Publicado: (2021)

Efficacy comparison of Kirschner-wire tension band and anchor loop plate in treatment of olecranon fracture
por: Du, Bing, et al.
Publicado: (2023)

Effects of different preservation on the mechanical properties of cortical bone under quasi-static and dynamic compression
por: Qiu, Jinlong, et al.
Publicado: (2023)

Suppression of AGTR1 Induces Cellular Senescence in Hepatocellular Carcinoma Through Inactivating ERK Signaling
por: Wang, Houhong, et al.
Publicado: (2022)

Kinematic and biomechanical responses of the spine to distraction surgery in children with early onset scoliosis: A 3-D finite element analysis
por: Pei, Baoqing, et al.
Publicado: (2022)

Treatment of Acute Wounds With Recombinant Human-Like Collagen and Recombinant Human-Like Fibronectin in C57BL/6 Mice Individually or in Combination
por: Dong, Yunqing, et al.
Publicado: (2022)

Electrochemical Microwell Plate to Study Electroactive Microorganisms in Parallel and Real-Time
por: Kuchenbuch, Anne, et al.
Publicado: (2022)

PLATERO: A calibration protocol for plate reader green fluorescence measurements
por: González-Cebrián, Alba, et al.
Publicado: (2023)

Biomechanics of PHILOS plates in Vancouver B1 periprosthetic femoral fracture
por: Yun, Changjun, et al.
Publicado: (2023)

Proteomic Reveals Reasons for Acquired Drug Resistance in Lung Cancer Derived Brain Metastasis Based on a Newly Established Multi-Organ Microfluidic Chip Model
por: Xu, Mingxin, et al.
Publicado: (2020)

Biomechanical comparative analysis of conventional pedicle screws and cortical bone trajectory fixation in the lumbar spine: An in vitro and finite element study
por: Pei, Baoqing, et al.
Publicado: (2023)

Construction of SARS-CoV-2 Virus-Like Particles by Mammalian Expression System
por: Xu, Ruodan, et al.
Publicado: (2020)

Characterization of an Amphiphilic Phosphonated Calixarene Carrier Loaded With Carboplatin and Paclitaxel: A Preliminary Study to Treat Colon Cancer in vitro and in vivo
por: Li, Meiying, et al.
Publicado: (2019)

Universal CRISPR/Cas12a-associated aptasensor suitable for rapid detection of small proteins with a plate reader
por: Li, Yi, et al.
Publicado: (2023)

Corrigendum: Construction of SARS-CoV-2 Virus-Like Particles by Mammalian Expression System
por: Xu, Ruodan, et al.
Publicado: (2020)

3D bioprinted hydrogel/polymer scaffold with factor delivery and mechanical support for growth plate injury repair
por: Fan, Minjie, et al.
Publicado: (2023)

In Silico Biomechanical Evaluation of WE43 Magnesium Plates for Mandibular Fracture Fixation
por: Orassi, Vincenzo, et al.
Publicado: (2022)

Flipped Well-Plate Hanging-Drop Technique for Growing Three-Dimensional Tumors
por: Jeong, Yoon, et al.
Publicado: (2022)

Synthesis and Assembly of Hepatitis B Virus-Like Particles in a Pichia pastoris Cell-Free System
por: Spice, Alex J., et al.
Publicado: (2020)

Development of Biomimetic Hepatic Lobule-Like Constructs on Silk-Collagen Composite Scaffolds for Liver Tissue Engineering
por: Guo, Lina, et al.
Publicado: (2022)

Editorial: The Application of Nanoengineering in Advanced Drug Delivery and Translational Research
por: Chen, Zhidong, et al.
Publicado: (2022)

Multimodal imaging of nano-assembled microspheres loaded with doxorubicin and Cisplatin for liver tumor therapy
por: He, Yiwei, et al.
Publicado: (2022)

Bioinspired Protein/Peptide Loaded 3D Printed PLGA Scaffold Promotes Bone Regeneration
por: Song, Xiaoliang, et al.
Publicado: (2022)

An in Silico Approach to Reveal the Nanodisc Formulation of Doxorubicin
por: Xu, Daiyun, et al.
Publicado: (2022)

Finite element analysis of different fixation methods of screws on absorbable plate for rib fractures
por: Xue, Hang, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_vnco1en1fsa48recg9kn4o49bc