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Application of 3D Hepatic Plate-Like Liver Model for Statin-Induced Hepatotoxicity Evaluation

Background: Drug-induced liver injury is one of the main reasons of withdrawals of drugs in postmarketing stages. However, an experimental model(s) which can accurately recapitulates liver functions and reflects the level of drug hepatotoxicity is lack. In this study, we assessed drug hepatotoxicity...

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Detalles Bibliográficos
Autores principales: Xu, Jiecheng, Pan, Daogang, Liao, Wei, Jia, Zhidong, Pan, Mingxin, Weng, Jun, Han, Xu, Li, Shao, Li, Yang, Liang, Kangyan, Zhou, Shuqin, Peng, Qing, Gao, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8968918/
https://www.ncbi.nlm.nih.gov/pubmed/35372314
http://dx.doi.org/10.3389/fbioe.2022.826093

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