Cargando…

Golgi Phosphoprotein 3 Promotes Colon Cancer Cell Metastasis Through STAT3 and Integrin α3 Pathways

Background: Golgi phosphoprotein 3 (GOLPH3) overexpression was recently reported to be associated with a poor clinical outcome in patients with colorectal cancer (CRC). However, the underlying molecular mechanism through which GOLPH3 promotes CRC metastasis remains poorly understood. Methods: In vit...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Anpei, Wang, Ruizhi, Cui, Ji, Gao, Ying, Yin, Zheng, Chen, Lianzhou, He, Meifang, Li, Wen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8968920/ https://www.ncbi.nlm.nih.gov/pubmed/35372504 http://dx.doi.org/10.3389/fmolb.2022.808152

Ejemplares similares

RIPK4 Suppresses the Invasion and Metastasis of Hepatocellular Carcinoma by Inhibiting the Phosphorylation of STAT3
por: Li, Haoran, et al.
Publicado: (2021)

Roles of Integrins in Gastrointestinal Cancer Metastasis
por: Hou, Sicong, et al.
Publicado: (2021)

Golgi phosphoprotein 3 induces autophagy and epithelial–mesenchymal transition to promote metastasis in colon cancer
por: Gong, Li-Yun, et al.
Publicado: (2022)

The Significance of Secreted Phosphoprotein 1 in Multiple Human Cancers
por: Wei, Tengteng, et al.
Publicado: (2020)

Application of Force to a Syndecan-4 Containing Complex With Thy-1–α(V)β(3) Integrin Accelerates Neurite Retraction
por: Burgos-Bravo, Francesca, et al.
Publicado: (2020)

MicroRNA-653-5p Promotes Gastric Cancer Proliferation and Metastasis by Targeting the SOCS6-STAT3 Pathway
por: Li, Zengliang, et al.
Publicado: (2021)

Sinomenine Suppresses Development of Hepatocellular Carcinoma Cells via Inhibiting MARCH1 and AMPK/STAT3 Signaling Pathway
por: Yang, Wei, et al.
Publicado: (2021)

Malate-Aspartate Shuttle Plays an Important Role in LPS-Induced Neuroinflammation of Mice Due to its Effect on STAT3 Phosphorylation
por: Zhou, Cuiyan, et al.
Publicado: (2021)

Ubiquitin-mediated degradation at the Golgi apparatus
por: Buzuk, Lana, et al.
Publicado: (2023)

The multiple cellular functions of the oncoprotein Golgi phosphoprotein 3
por: Sechi, Stefano, et al.
Publicado: (2015)

Independent duplications of the Golgi phosphoprotein 3 oncogene in birds
por: Opazo, Juan C., et al.
Publicado: (2021)

Golgi Phosphoprotein 3 Inhibits the Apoptosis of Human Glioma Cells in Part by Downregulating N-myc Downstream Regulated Gene 1
por: Li, Xin, et al.
Publicado: (2016)

Golgi phosphoprotein 3 promotes angiogenesis and sorafenib resistance in hepatocellular carcinoma via upregulating exosomal miR-494-3p
por: Gao, Ying, et al.
Publicado: (2022)

RAC3 Promotes Proliferation, Migration and Invasion via PYCR1/JAK/STAT Signaling in Bladder Cancer
por: Cheng, Chuanyu, et al.
Publicado: (2020)

STAT3 and IL-6 Contribute to Corticosteroid Resistance in an OVA and Ozone-induced Asthma Model with Neutrophil Infiltration
por: Xue, Yishu, et al.
Publicado: (2021)

Indian Ethnomedicinal Phytochemicals as Promising Inhibitors of RNA-Binding Domain of SARS-CoV-2 Nucleocapsid Phosphoprotein: An In Silico Study
por: Muthumanickam, Sankar, et al.
Publicado: (2021)

Golgi Phosphoprotein 3 Regulates the Physical Association of Glycolipid Glycosyltransferases †
por: Ruggiero, Fernando M., et al.
Publicado: (2022)

Differential fibril morphologies and thermostability determine functional roles of Staphylococcus aureus PSMα1 and PSMα3
por: Rayan, Bader, et al.
Publicado: (2023)

miR-124-3p Suppresses the Invasiveness and Metastasis of Hepatocarcinoma Cells via Targeting CRKL
por: Majid, Abbasi, et al.
Publicado: (2020)

Biosynthesis of α-Gal Epitopes (Galα1-3Galβ1-4GlcNAc-R) and Their Unique Potential in Future α-Gal Therapies
por: Galili, Uri
Publicado: (2021)

Golgi phosphoprotein 3 sensitizes the tumour suppression effect of gefitinib on gliomas
por: Wang, Xu, et al.
Publicado: (2019)

Diagnostic Utility of Serum Golgi Phosphoprotein 3 in Bladder Cancer Patients
por: Lu, Jianlei, et al.
Publicado: (2019)

CORO1C is Associated With Poor Prognosis and Promotes Metastasis Through PI3K/AKT Pathway in Colorectal Cancer
por: Wang, Zongxia, et al.
Publicado: (2021)

Structural insights into the functional roles of 14-3-3 proteins
por: Obsilova, Veronika, et al.
Publicado: (2022)

Corrigendum: CORO1C is Associated with Poor Prognosis and Promotes Metastasis Through PI3K/AKT Pathway in Colorectal Cancer
por: Wang, Zongxia, et al.
Publicado: (2021)

7,3′,4′-Trihydroxyisoflavone, a Metabolite of the Soy Isoflavone Daidzein, Suppresses α-Melanocyte-Stimulating Hormone-Induced Melanogenesis by Targeting Melanocortin 1 Receptor
por: Kim, Ji Hye, et al.
Publicado: (2020)

MiR-490-3p Silences CDK1 and Inhibits the Proliferation of Colon Cancer Through an LLPS-Dependent miRISC System
por: Qin, Da, et al.
Publicado: (2021)

Structure-Function Relationship of the Disintegrin Family: Sequence Signature and Integrin Interaction
por: Vasconcelos, Ariana A., et al.
Publicado: (2021)

Alternative Splicing of MXD3 and Its Regulation of MXD3 Levels in Glioblastoma
por: Ngo, Tin, et al.
Publicado: (2019)

Contemporary biophysical approaches for studying 14-3-3 protein-protein interactions
por: Thurairajah, Bethany, et al.
Publicado: (2022)

Isomer-Specific Monitoring of Sialylated N-Glycans Reveals Association of α2,3-Linked Sialic Acid Epitope With Behcet’s Disease
por: Seo, Nari, et al.
Publicado: (2021)

Long noncoding RNA maternally expressed gene 3 improves trophoblast dysfunction and inflammation in preeclampsia through the Wnt/β-Catenin/nod-like receptor pyrin domain-containing 3 axis
por: Liang, Yue, et al.
Publicado: (2022)

Structural Details of BH3 Motifs and BH3-Mediated Interactions: an Updated Perspective
por: Sora, Valentina, et al.
Publicado: (2022)

Adhesions Assemble!—Autoinhibition as a Major Regulatory Mechanism of Integrin-Mediated Adhesion
por: Khan, Rejina B., et al.
Publicado: (2019)

Characterization of Integrin Molecular Tension of Human Breast Cancer Cells on Anisotropic Nanopatterns
por: Kim, Kyung Ah, et al.
Publicado: (2022)

Proteomic profiling of eIF3a conditional knockout mice
por: Zhuo, Wei, et al.
Publicado: (2023)

D-3-Phosphoglycerate Dehydrogenase
por: Grant, Gregory A.
Publicado: (2018)

Clinical Value and Potential Mechanisms of Oxysterol-Binding Protein Like 3 (OSBPL3) in Human Tumors
por: Hao, Na, et al.
Publicado: (2021)

Prognostic value, immune signature and molecular mechanisms of the APOBEC family members APOBEC1, APOBEC3A, APOBEC3G and APOBEC3H in pancreatic adenocarcinoma
por: Duan, Yunjie, et al.
Publicado: (2022)

Matrin3: Disorder and ALS Pathogenesis
por: Salem, Ahmed, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ta6v74hee71ge2nqo9dn9q3sbl