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The Challenge of Identifying Representative Samples in Research Involving Minority Participants

Determining participants' demographics, cognition, and functional performance by race is crucial to understanding disparities in clinical research on Alzheimer’s disease. We compared demographic and performance variables between Black/African American (B/AA; N=30; 41%) and White participants (N...

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Autores principales: Pilonieta, Giovanna, Geldmacher, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8969071/
http://dx.doi.org/10.1093/geroni/igab046.381
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author Pilonieta, Giovanna
Geldmacher, David
author_facet Pilonieta, Giovanna
Geldmacher, David
author_sort Pilonieta, Giovanna
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description Determining participants' demographics, cognition, and functional performance by race is crucial to understanding disparities in clinical research on Alzheimer’s disease. We compared demographic and performance variables between Black/African American (B/AA; N=30; 41%) and White participants (N=43, 59%) in the UAB Alzheimer's Disease Center. Among 73 participants, 38 (52%) were women, mean age was 65.7 (SD 9.47), and mean education was 16 (2.31) years. Significant differences in gender proportions across race groups were observed. B/AA women represented 70 % of their race group, white women represented 39.5 %. There were no statistically significant differences in age, education, cognitive or functional severity, reasons to participate in research, referral source, objective measures of cognition, or informant-rated daily function by race group. In conclusion, despite 50% oversampling of B/AA participants compared to the State population, no differences in cognitive and functional performance at the time of enrollment were associated with race.
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spelling pubmed-89690712022-04-01 The Challenge of Identifying Representative Samples in Research Involving Minority Participants Pilonieta, Giovanna Geldmacher, David Innov Aging Abstracts Determining participants' demographics, cognition, and functional performance by race is crucial to understanding disparities in clinical research on Alzheimer’s disease. We compared demographic and performance variables between Black/African American (B/AA; N=30; 41%) and White participants (N=43, 59%) in the UAB Alzheimer's Disease Center. Among 73 participants, 38 (52%) were women, mean age was 65.7 (SD 9.47), and mean education was 16 (2.31) years. Significant differences in gender proportions across race groups were observed. B/AA women represented 70 % of their race group, white women represented 39.5 %. There were no statistically significant differences in age, education, cognitive or functional severity, reasons to participate in research, referral source, objective measures of cognition, or informant-rated daily function by race group. In conclusion, despite 50% oversampling of B/AA participants compared to the State population, no differences in cognitive and functional performance at the time of enrollment were associated with race. Oxford University Press 2021-12-17 /pmc/articles/PMC8969071/ http://dx.doi.org/10.1093/geroni/igab046.381 Text en © The Author(s) 2021. Published by Oxford University Press on behalf of The Gerontological Society of America. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Abstracts
Pilonieta, Giovanna
Geldmacher, David
The Challenge of Identifying Representative Samples in Research Involving Minority Participants
title The Challenge of Identifying Representative Samples in Research Involving Minority Participants
title_full The Challenge of Identifying Representative Samples in Research Involving Minority Participants
title_fullStr The Challenge of Identifying Representative Samples in Research Involving Minority Participants
title_full_unstemmed The Challenge of Identifying Representative Samples in Research Involving Minority Participants
title_short The Challenge of Identifying Representative Samples in Research Involving Minority Participants
title_sort challenge of identifying representative samples in research involving minority participants
topic Abstracts
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8969071/
http://dx.doi.org/10.1093/geroni/igab046.381
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