Cargando…

Subclonal heterogeneity sheds light on the transformation trajectory in IGLV3-21(R110) chronic lymphocytic leukemia

Detalles Bibliográficos
Autores principales:	Paschold, Lisa, Simnica, Donjete, Brito, Ramon Benitez, Zhang, Tianjiao, Schultheiß, Christoph, Dierks, Christine, Binder, Mascha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Correspondence
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8969164/ https://www.ncbi.nlm.nih.gov/pubmed/35354800 http://dx.doi.org/10.1038/s41408-022-00650-4

Ejemplares similares

Maturation trajectories and transcriptional landscape of plasmablasts and autoreactive B cells in COVID-19
por: Schultheiß, Christoph, et al.
Publicado: (2021)

PD-L1 Amino Acid Position 88 Represents a Hotspot for PD-L1 Stability With Relevance for PD-L1 Inhibition
por: Claaß, Luise Victoria, et al.
Publicado: (2022)

Rapid Hypermutation B Cell Trajectory Recruits Previously Primed B Cells Upon Third SARS-Cov-2 mRNA Vaccination
por: Paschold, Lisa, et al.
Publicado: (2022)

Azacitidine-induced reconstitution of the bone marrow T cell repertoire is associated with superior survival in AML patients
por: Grimm, Juliane, et al.
Publicado: (2022)

Prevalence of IGLV3-21(R110) among familial CLL: a retrospective study of 45 cases
por: Armand, Marine, et al.
Publicado: (2022)

Prognosis of IGLV3-21(R110) chronic lymphocytic leukemia after chemotherapy-based treatment in a real-world analysis
por: Hengeveld, Paul J., et al.
Publicado: (2023)

Targeting the Mutational Landscape of Bystander Cells: Drug-Promoted Blood Cancer From High-Prevalence Pre-neoplasias in Patients on BRAF Inhibitors
por: Simnica, Donjete, et al.
Publicado: (2020)

PD-L1 targeting and subclonal immune escape mediated by PD-L1 mutations in metastatic colorectal cancer
por: Stein, Alexander, et al.
Publicado: (2021)

Evolutionary clonal trajectories in nodular lymphocyte-predominant Hodgkin lymphoma with high risk of transformation
por: Paschold, Lisa, et al.
Publicado: (2021)

Next-Generation Sequencing of T and B Cell Receptor Repertoires from COVID-19 Patients Showed Signatures Associated with Severity of Disease
por: Schultheiß, Christoph, et al.
Publicado: (2020)

Identification of a unique TCR repertoire, consistent with a superantigen selection process in Children with Multi-system Inflammatory Syndrome
por: Porritt, Rebecca A, et al.
Publicado: (2020)

Landscape of T‐cell repertoires with public COVID‐19‐associated T‐cell receptors in pre‐pandemic risk cohorts
por: Simnica, Donjete, et al.
Publicado: (2021)

High-Throughput Immunogenetics Reveals a Lack of Physiological T Cell Clusters in Patients With Autoimmune Cytopenias
por: Simnica, Donjete, et al.
Publicado: (2019)

SLAMF receptors negatively regulate B cell receptor signaling in chronic lymphocytic leukemia via recruitment of prohibitin-2
por: von Wenserski, Lisa, et al.
Publicado: (2020)

Immune signatures in variant syndromes of primary biliary cholangitis and autoimmune hepatitis
por: Schultheiß, Christoph, et al.
Publicado: (2023)

Circulating Tumor DNA in Gastric and Gastroesophageal Junction Cancer
por: Paschold, Lisa, et al.
Publicado: (2022)

IGLV3-21*01 is an inherited risk factor for CLL through the acquisition of a single-point mutation enabling autonomous BCR signaling
por: Maity, Palash C., et al.
Publicado: (2020)

Subclonal heterogeneity and evolution in breast cancer
por: Mavrommati, Ioanna, et al.
Publicado: (2021)

Liquid biomarkers of macrophage dysregulation and circulating spike protein illustrate the biological heterogeneity in patients with post‐acute sequelae of COVID‐19
por: Schultheiß, Christoph, et al.
Publicado: (2022)

Deep sequencing of bone marrow microenvironments of patients with del(5q) myelodysplastic syndrome reveals imprints of antigenic selection as well as generation of novel T-cell clusters as a response pattern to lenalidomide
por: Mährle, Thorben, et al.
Publicado: (2019)

Overcoming unintended immunogenicity in immunocompetent mouse models of metastasis: the case of GFP
por: Schultheiß, Christoph, et al.
Publicado: (2022)

First-line treatment of unresectable or metastatic HER2 positive esophagogastric adenocarcinoma: liquid biomarker analysis of the phase 2 INTEGA trial
por: Paschold, Lisa, et al.
Publicado: (2023)

Characterization of the T cell receptor repertoire and melanoma tumor microenvironment upon combined treatment with ipilimumab and hTERT vaccination
por: Ellingsen, Espen Basmo, et al.
Publicado: (2022)

Translational analysis and final efficacy of the AVETUX trial – Avelumab, cetuximab and FOLFOX in metastatic colorectal cancer
por: Tintelnot, Joseph, et al.
Publicado: (2022)

Detecting copy number status and uncovering subclonal markers in heterogeneous tumor biopsies
por: Parisi, Fabio, et al.
Publicado: (2011)

Tumor cell heterogeneity maintained by cooperating subclones in Wnt-driven mammary cancers
por: Cleary, Allison S., et al.
Publicado: (2014)

Heterogeneity and proliferation of invasive cancer subclones in game theory models of the Warburg effect
por: Archetti, M.
Publicado: (2015)

DENDRO: genetic heterogeneity profiling and subclone detection by single-cell RNA sequencing
por: Zhou, Zilu, et al.
Publicado: (2020)

B cells in autoimmune hepatitis: bystanders or central players?
por: Schultheiß, Christoph, et al.
Publicado: (2022)

Unravelling subclonal heterogeneity and aggressive disease states in TNBC through single-cell RNA-seq
por: Karaayvaz, Mihriban, et al.
Publicado: (2018)

Xenograft and cell culture models of Sézary syndrome reveal cell of origin diversity and subclonal heterogeneity
por: Poglio, Sandrine, et al.
Publicado: (2020)

Molecular profiling and specific targeting of gemcitabine-resistant subclones in heterogeneous pancreatic cancer cell populations
por: Färber, Benedikt, et al.
Publicado: (2023)

Circulating Tumor DNA in Head and Neck Squamous Cell Carcinoma
por: Brandt, Anna, et al.
Publicado: (2023)

Accurate Identification of Subclones in Tumor Genomes
por: Ahmadinejad, Navid, et al.
Publicado: (2022)

Malignant subclone drives metastasis of genetically and phenotypically heterogenous cell clusters through fibrotic niche generation
por: Kok, Sau Yee, et al.
Publicado: (2021)

Single-cell RNA sequencing revealed subclonal heterogeneity and gene signatures of gemcitabine sensitivity in pancreatic cancer
por: Hou, Zelin, et al.
Publicado: (2023)

Impact of bone marrow involvement on outcome in relapsed and refractory transplant eligible diffuse large B-cell lymphoma and transformed indolent lymphoma
por: Terziev, Denis, et al.
Publicado: (2020)

Biased estimates of clonal evolution and subclonal heterogeneity can arise from PCR duplicates in deep sequencing experiments
por: Smith, Erin N, et al.
Publicado: (2014)

Analytical subcloning of a clonal cell line demonstrates cellular heterogeneity that does not impact process consistency or robustness
por: Scarcelli, John J., et al.
Publicado: (2018)

Deconstructing the intra-tumor subclonal heterogeneity of lung synchronous ground-glass nodules using whole-genome sequencing
por: Ren, Yijiu, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_qj9uufs8ai820g8sh3s03009v8