RNA sequencing identifies novel regulated IRE1-dependent decay targets that affect multiple myeloma survival and proliferation

BACKGROUND: IRE1 is an unfolded protein response (UPR) sensor with kinase and endonuclease activity. It plays a central role in the endoplasmic reticulum (ER) stress response through unconventional splicing of XBP1 mRNA and regulated IRE1-dependent decay (RIDD). Multiple myeloma (MM) cells are known...

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Detalles Bibliográficos
Autores principales: Quwaider, Dalia, Corchete, Luis A., Martín-Izquierdo, Marta, Hernández-Sánchez, Jesús M., Rojas, Elizabeta A., Cardona-Benavides, Ignacio J., García-Sanz, Ramón, Herrero, Ana B., Gutiérrez, Norma C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8969279/
https://www.ncbi.nlm.nih.gov/pubmed/35361260
http://dx.doi.org/10.1186/s40164-022-00271-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8969279/
https://www.ncbi.nlm.nih.gov/pubmed/35361260
http://dx.doi.org/10.1186/s40164-022-00271-4

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