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Novel Cell-Based Assay for Alpha-3 Nicotinic Receptor Antibodies Detects Antibodies Exclusively in Autoimmune Autonomic Ganglionopathy

BACKGROUND AND OBJECTIVES: Autoantibodies against α3-subunit–containing nicotinic acetylcholine receptors (α3-nAChRs), usually measured by radioimmunoprecipitation assay (RIPA), are detected in patients with autoimmune autonomic ganglionopathy (AAG). However, low α3-nAChR antibody levels are frequen...

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Detalles Bibliográficos
Autores principales: Karagiorgou, Katerina, Dandoulaki, Maria, Mantegazza, Renato, Andreetta, Francesca, Furlan, Raffaello, Lindstrom, Jon, Zisimopoulou, Paraskevi, Chroni, Elisabeth, Kokotis, Panagiotis, Anagnostou, Evangelos, Tzanetakos, Dimitrios, Breza, Marianthi, Katsarou, Zoe, Amoiridis, Georgios, Mastorodemos, Vasileios, Bregianni, Marianna, Bonakis, Anastasios, Tsivgoulis, Georgios, Voumvourakis, Konstantinos, Tzartos, Socrates, Tzartos, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8969289/
https://www.ncbi.nlm.nih.gov/pubmed/35351814
http://dx.doi.org/10.1212/NXI.0000000000001162