METTL3 enhances NSD2 mRNA stability to reduce renal impairment and interstitial fibrosis in mice with diabetic nephropathy

BACKGROUND: Nuclear receptor-binding SET domain protein 2 (NSD2) is a histone methyltransferase that has been demonstrated to regulate insulin secretion and glucose concentration. This study focused on the role of NSD2 in the renal impairment during diabetic nephropathy (DN). METHODS: Serum NSD2 lev...

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Detalles Bibliográficos
Autores principales: Tang, Weiming, Zhao, Yilin, Zhang, Hui, Peng, Ying, Rui, Zhilian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8969340/
https://www.ncbi.nlm.nih.gov/pubmed/35354439
http://dx.doi.org/10.1186/s12882-022-02753-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8969340/
https://www.ncbi.nlm.nih.gov/pubmed/35354439
http://dx.doi.org/10.1186/s12882-022-02753-3

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