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METTL3 enhances NSD2 mRNA stability to reduce renal impairment and interstitial fibrosis in mice with diabetic nephropathy

BACKGROUND: Nuclear receptor-binding SET domain protein 2 (NSD2) is a histone methyltransferase that has been demonstrated to regulate insulin secretion and glucose concentration. This study focused on the role of NSD2 in the renal impairment during diabetic nephropathy (DN). METHODS: Serum NSD2 lev...

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Detalles Bibliográficos
Autores principales:	Tang, Weiming, Zhao, Yilin, Zhang, Hui, Peng, Ying, Rui, Zhilian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8969340/ https://www.ncbi.nlm.nih.gov/pubmed/35354439 http://dx.doi.org/10.1186/s12882-022-02753-3

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