A Role of Caveolae in Trabecular Meshwork Mechanosensing and Contractile Tone

Polymorphisms in the CAV1/2 gene loci impart increased risk for primary open-angle glaucoma (POAG). CAV1 encodes caveolin-1 (Cav1), which is required for biosynthesis of plasma membrane invaginations called caveolae. Cav1 knockout mice exhibit elevated intraocular pressure (IOP) and decreased outflo...

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Detalles Bibliográficos
Autores principales: De Ieso, Michael L., Kuhn, Megan, Bernatchez, Pascal, Elliott, Michael H., Stamer, W. Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8969750/
https://www.ncbi.nlm.nih.gov/pubmed/35372369
http://dx.doi.org/10.3389/fcell.2022.855097

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8969750/
https://www.ncbi.nlm.nih.gov/pubmed/35372369
http://dx.doi.org/10.3389/fcell.2022.855097

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