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A Role of Caveolae in Trabecular Meshwork Mechanosensing and Contractile Tone

Polymorphisms in the CAV1/2 gene loci impart increased risk for primary open-angle glaucoma (POAG). CAV1 encodes caveolin-1 (Cav1), which is required for biosynthesis of plasma membrane invaginations called caveolae. Cav1 knockout mice exhibit elevated intraocular pressure (IOP) and decreased outflo...

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Detalles Bibliográficos
Autores principales:	De Ieso, Michael L., Kuhn, Megan, Bernatchez, Pascal, Elliott, Michael H., Stamer, W. Daniel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8969750/ https://www.ncbi.nlm.nih.gov/pubmed/35372369 http://dx.doi.org/10.3389/fcell.2022.855097

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