Cargando…

Cell Senescence as a Mediator of Age-Dependent Brain Inflammation

Cellular senescence and inflammation are interconnected causes and consequences of tissue aging. Here, we implemented orthogonal approaches to study their interaction in steady-state mature and aged mouse brain. Using single cell sequencing, we identified a putative senescent microglial population,...

Descripción completa

Detalles Bibliográficos
Autores principales: Schafer, Marissa, Zhang, Xu, Pearsall, Vesselina, LeBrasseur, Nathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8969832/
http://dx.doi.org/10.1093/geroni/igab046.953