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Cell Senescence as a Mediator of Age-Dependent Brain Inflammation
Cellular senescence and inflammation are interconnected causes and consequences of tissue aging. Here, we implemented orthogonal approaches to study their interaction in steady-state mature and aged mouse brain. Using single cell sequencing, we identified a putative senescent microglial population,...
Autores principales: | Schafer, Marissa, Zhang, Xu, Pearsall, Vesselina, LeBrasseur, Nathan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8969832/ http://dx.doi.org/10.1093/geroni/igab046.953 |
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