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Therapeutic management of a symptomatic Kaposi’s sarcoma patient with renal failure undergoing haemodialysis: A case report

Kaposi’s sarcoma (KS) is a rare inflammation- based vascular cancer involving the skin. The viral aetiology of KS is the Human Herpesvirus 8. KS may be frequently diagnosed in immunosuppressed kidneytransplanted patients, while is less common in patients with dialysis. It is known that various immun...

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Autores principales: Passarelli, Anna, Galdo, Giovanna, Pellegrino, Teresa, Roviello, Giandomenico, Aieta, Michele, Aviello, Gabriella, Conca, Raffaele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8969873/
https://www.ncbi.nlm.nih.gov/pubmed/35371419
http://dx.doi.org/10.4081/dr.2022.9113
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author Passarelli, Anna
Galdo, Giovanna
Pellegrino, Teresa
Roviello, Giandomenico
Aieta, Michele
Aviello, Gabriella
Conca, Raffaele
author_facet Passarelli, Anna
Galdo, Giovanna
Pellegrino, Teresa
Roviello, Giandomenico
Aieta, Michele
Aviello, Gabriella
Conca, Raffaele
author_sort Passarelli, Anna
collection PubMed
description Kaposi’s sarcoma (KS) is a rare inflammation- based vascular cancer involving the skin. The viral aetiology of KS is the Human Herpesvirus 8. KS may be frequently diagnosed in immunosuppressed kidneytransplanted patients, while is less common in patients with dialysis. It is known that various immunological abnormalities can lead to impaired immune status in uremic patients. It is noteworthy that despite the incidence of KS in patients with renal impairment, only few cases have reported efficacy and safety profile of KS targeting anti-cancer drugs in this kidney disease population. Herein, we report the first case of a symptomatic KS patient with renal disease in haemodialysis and focus on its therapeutic management. We also review the main data available from literature regarding the safety of KS therapy in dialysis patients.
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spelling pubmed-89698732022-04-01 Therapeutic management of a symptomatic Kaposi’s sarcoma patient with renal failure undergoing haemodialysis: A case report Passarelli, Anna Galdo, Giovanna Pellegrino, Teresa Roviello, Giandomenico Aieta, Michele Aviello, Gabriella Conca, Raffaele Dermatol Reports Case Report Kaposi’s sarcoma (KS) is a rare inflammation- based vascular cancer involving the skin. The viral aetiology of KS is the Human Herpesvirus 8. KS may be frequently diagnosed in immunosuppressed kidneytransplanted patients, while is less common in patients with dialysis. It is known that various immunological abnormalities can lead to impaired immune status in uremic patients. It is noteworthy that despite the incidence of KS in patients with renal impairment, only few cases have reported efficacy and safety profile of KS targeting anti-cancer drugs in this kidney disease population. Herein, we report the first case of a symptomatic KS patient with renal disease in haemodialysis and focus on its therapeutic management. We also review the main data available from literature regarding the safety of KS therapy in dialysis patients. PAGEPress Publications, Pavia, Italy 2021-10-29 /pmc/articles/PMC8969873/ /pubmed/35371419 http://dx.doi.org/10.4081/dr.2022.9113 Text en ©Copyright: the Author(s) https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution Noncommercial License (by-nc 4.0) which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.
spellingShingle Case Report
Passarelli, Anna
Galdo, Giovanna
Pellegrino, Teresa
Roviello, Giandomenico
Aieta, Michele
Aviello, Gabriella
Conca, Raffaele
Therapeutic management of a symptomatic Kaposi’s sarcoma patient with renal failure undergoing haemodialysis: A case report
title Therapeutic management of a symptomatic Kaposi’s sarcoma patient with renal failure undergoing haemodialysis: A case report
title_full Therapeutic management of a symptomatic Kaposi’s sarcoma patient with renal failure undergoing haemodialysis: A case report
title_fullStr Therapeutic management of a symptomatic Kaposi’s sarcoma patient with renal failure undergoing haemodialysis: A case report
title_full_unstemmed Therapeutic management of a symptomatic Kaposi’s sarcoma patient with renal failure undergoing haemodialysis: A case report
title_short Therapeutic management of a symptomatic Kaposi’s sarcoma patient with renal failure undergoing haemodialysis: A case report
title_sort therapeutic management of a symptomatic kaposi’s sarcoma patient with renal failure undergoing haemodialysis: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8969873/
https://www.ncbi.nlm.nih.gov/pubmed/35371419
http://dx.doi.org/10.4081/dr.2022.9113
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