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A Fucosylated Glycopeptide as a Candidate Biomarker for Early Diagnosis of NASH Hepatocellular Carcinoma Using a Stepped HCD Method and PRM Evaluation

Aberrant specific N-glycosylation, especially the increase in fucosylation on specific peptide sites of serum proteins have been investigated as potential markers for diagnosis of nonalcoholic steatohepatitis (NASH)-related HCC. We have combined a workflow involving broad scale marker discovery in s...

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Detalles Bibliográficos
Autores principales: Lin, Yu, Zhang, Jie, Arroyo, Ana, Singal, Amit G., Parikh, Neehar D., Lubman, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8970044/
https://www.ncbi.nlm.nih.gov/pubmed/35372033
http://dx.doi.org/10.3389/fonc.2022.818001