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Transcriptome Analysis Reveal Candidate Genes and Pathways Responses to Lactate Dehydrogenase Inhibition (Oxamate) in Hyperglycemic Human Renal Proximal Epithelial Tubular Cells

Diabetic kidney disease (DKD) is the leading cause of both chronic kidney disease (CKD) and end-stage renal disease (ESRD). Previous studies showed that oxamate could regulate glycemic homeostasis and impacted mitochondria respiration in a hyperglycemia-dependent manner in the rat proximal tubular c...

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Detalles Bibliográficos
Autores principales:	Wang, Zhimin, Hao, Dan, Fang, Dong, Yu, Jiating, Wang, Xiao, Qin, Guijun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8970056/ https://www.ncbi.nlm.nih.gov/pubmed/35370938 http://dx.doi.org/10.3389/fendo.2022.785605

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