Suppression of human and simian immunodeficiency virus replication with the CCR5-specific antibody Leronlimab in two species

The CCR5-specific antibody Leronlimab is being investigated as a novel immunotherapy that can suppress HIV replication with minimal side effects. Here we studied the virological and immunological consequences of Leronlimab in chronically CCR5-tropic HIV-1 infected humans (n = 5) on suppressive antir...

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Detalles Bibliográficos
Autores principales: Chang, Xiao L., Reed, Jason S., Webb, Gabriela M., Wu, Helen L., Le, Jimmy, Bateman, Katherine B., Greene, Justin M., Pessoa, Cleiton, Waytashek, Courtney, Weber, Whitney C., Hwang, Joseph, Fischer, Miranda, Moats, Cassandra, Shiel, Oriene, Bochart, Rachele M., Crank, Hugh, Siess, Don, Giobbi, Travis, Torgerson, Jeffrey, Agnor, Rebecca, Gao, Lina, Dhody, Kush, Lalezari, Jacob P., Bandar, Ivo Sah, Carnate, Alnor M., Pang, Alina S., Corley, Michael J., Kelly, Scott, Pourhassan, Nader, Smedley, Jeremy, Bimber, Benjamin N., Hansen, Scott G., Ndhlovu, Lishomwa C., Sacha, Jonah B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8970399/
https://www.ncbi.nlm.nih.gov/pubmed/35358290
http://dx.doi.org/10.1371/journal.ppat.1010396

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