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Evolution of Molecular Targeted Cancer Therapy: Mechanisms of Drug Resistance and Novel Opportunities Identified by CRISPR-Cas9 Screening
Molecular targeted therapy has revolutionized the landscape of cancer treatment due to better therapeutic responses and less systemic toxicity. However, therapeutic resistance is a major challenge in clinical settings that hinders continuous clinical benefits for cancer patients. In this regard, unr...
Autores principales: | Hou, Jue, He, Zongsheng, Liu, Tian, Chen, Dongfeng, Wang, Bin, Wen, Qinglian, Zheng, Xi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8970599/ https://www.ncbi.nlm.nih.gov/pubmed/35372044 http://dx.doi.org/10.3389/fonc.2022.755053 |
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