Sepsis promotes splenic production of a protective platelet pool with high CD40 ligand expression

Platelets have a wide range of functions including critical roles in hemostasis, thrombosis, and immunity. We hypothesized that during acute inflammation, such as in life-threatening sepsis, there are fundamental changes in the sites of platelet production and phenotypes of resultant platelets. Here...

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Detalles Bibliográficos
Autores principales: Valet, Colin, Magnen, Mélia, Qiu, Longhui, Cleary, Simon J., Wang, Kristin M., Ranucci, Serena, Grockowiak, Elodie, Boudra, Rafik, Conrad, Catharina, Seo, Yurim, Calabrese, Daniel R., Greenland, John R., Leavitt, Andrew D., Passegué, Emmanuelle, Méndez-Ferrer, Simón, Swirski, Filip K., Looney, Mark R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8970674/
https://www.ncbi.nlm.nih.gov/pubmed/35192546
http://dx.doi.org/10.1172/JCI153920

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