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Single-cell RNA sequencing reveals induction of distinct trained-immunity programs in human monocytes

Trained immunity refers to the long-lasting memory traits of innate immunity. Recent studies have shown that trained immunity is orchestrated by sustained changes in epigenetic marks and metabolic pathways, leading to an altered transcriptional response to a second challenge. However, the potential...

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Detalles Bibliográficos
Autores principales:	Zhang, Bowen, Moorlag, Simone J.C.F.M, Dominguez-Andres, Jorge, Bulut, Özlem, Kilic, Gizem, Liu, Zhaoli, van Crevel, Reinout, Xu, Cheng-Jian, Joosten, Leo A.B., Netea, Mihai G., Li, Yang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8970681/ https://www.ncbi.nlm.nih.gov/pubmed/35133977 http://dx.doi.org/10.1172/JCI147719

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