The HIV-1 proviral landscape reveals that Nef contributes to HIV-1 persistence in effector memory CD4(+) T cells

Despite long-term antiretroviral therapy (ART), HIV-1 persists within a reservoir of CD4(+) T cells that contribute to viral rebound if treatment is interrupted. Identifying the cellular populations that contribute to the HIV-1 reservoir and understanding the mechanisms of viral persistence are nece...

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Detalles Bibliográficos
Autores principales: Duette, Gabriel, Hiener, Bonnie, Morgan, Hannah, Mazur, Fernando G., Mathivanan, Vennila, Horsburgh, Bethany A., Fisher, Katie, Tong, Orion, Lee, Eunok, Ahn, Haelee, Shaik, Ansari, Fromentin, Rémi, Hoh, Rebecca, Bacchus-Souffan, Charline, Nasr, Najla, Cunningham, Anthony L., Hunt, Peter W., Chomont, Nicolas, Turville, Stuart G., Deeks, Steven G., Kelleher, Anthony D., Schlub, Timothy E., Palmer, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8970682/
https://www.ncbi.nlm.nih.gov/pubmed/35133986
http://dx.doi.org/10.1172/JCI154422

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