A self-amplifying RNA vaccine protects against SARS-CoV-2 (D614G) and Alpha variant of concern (B.1.1.7) in a transmission-challenge hamster model

Vaccines for SARS-CoV-2 have been hugely successful in alleviating hospitalization and deaths caused by the newly emerged coronavirus that is the cause of COVID. However, although the parentally administered vaccines are very effective at reducing severe disease, they do not induce sterilizing immun...

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Detalles Bibliográficos
Autores principales: Frise, Rebecca, Baillon, Laury, Zhou, Jie, Kugathasan, Ruthiran, Peacock, Thomas P., Brown, Jonathan C., Samnuan, Karnyart, McKay, Paul F., Shattock, Robin J., Barclay, Wendy S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Ltd. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8971064/
https://www.ncbi.nlm.nih.gov/pubmed/35396165
http://dx.doi.org/10.1016/j.vaccine.2022.03.064

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