Effects of Digoxin in Heart Failure (HF) With Reduced Ejection Fraction (EF)

In this review, we evaluated the literature on the benefits and deleterious effects of digoxin in heart failure (HF) with reduced ejection fraction (EF). Although digoxin was considered an effective treatment for HF, the supporting evidence is conflicting. Before the conventional use of modern HF th...

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Detalles Bibliográficos
Autores principales: Parikh, Riya R, Patel, Khushbu R, Pergolizzi, Joseph V, Breve, Frank, Magnusson, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Cardiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8971068/
https://www.ncbi.nlm.nih.gov/pubmed/35371861
http://dx.doi.org/10.7759/cureus.22778
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author Parikh, Riya R
Patel, Khushbu R
Pergolizzi, Joseph V
Breve, Frank
Magnusson, Peter
author_facet Parikh, Riya R
Patel, Khushbu R
Pergolizzi, Joseph V
Breve, Frank
Magnusson, Peter
author_sort Parikh, Riya R
collection PubMed
description In this review, we evaluated the literature on the benefits and deleterious effects of digoxin in heart failure (HF) with reduced ejection fraction (EF). Although digoxin was considered an effective treatment for HF, the supporting evidence is conflicting. Before the conventional use of modern HF therapies, digoxin was widely used for symptomatic relief on these patients. Further randomized trials are required to reach a definite conclusion about its efficacy and safety in patients experiencing HF with a reduced EF (HFrEF).
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spelling pubmed-89710682022-04-01 Effects of Digoxin in Heart Failure (HF) With Reduced Ejection Fraction (EF) Parikh, Riya R Patel, Khushbu R Pergolizzi, Joseph V Breve, Frank Magnusson, Peter Cureus Cardiology In this review, we evaluated the literature on the benefits and deleterious effects of digoxin in heart failure (HF) with reduced ejection fraction (EF). Although digoxin was considered an effective treatment for HF, the supporting evidence is conflicting. Before the conventional use of modern HF therapies, digoxin was widely used for symptomatic relief on these patients. Further randomized trials are required to reach a definite conclusion about its efficacy and safety in patients experiencing HF with a reduced EF (HFrEF). Cureus 2022-03-02 /pmc/articles/PMC8971068/ /pubmed/35371861 http://dx.doi.org/10.7759/cureus.22778 Text en Copyright © 2022, Parikh et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Cardiology
Parikh, Riya R
Patel, Khushbu R
Pergolizzi, Joseph V
Breve, Frank
Magnusson, Peter
Effects of Digoxin in Heart Failure (HF) With Reduced Ejection Fraction (EF)
title Effects of Digoxin in Heart Failure (HF) With Reduced Ejection Fraction (EF)
title_full Effects of Digoxin in Heart Failure (HF) With Reduced Ejection Fraction (EF)
title_fullStr Effects of Digoxin in Heart Failure (HF) With Reduced Ejection Fraction (EF)
title_full_unstemmed Effects of Digoxin in Heart Failure (HF) With Reduced Ejection Fraction (EF)
title_short Effects of Digoxin in Heart Failure (HF) With Reduced Ejection Fraction (EF)
title_sort effects of digoxin in heart failure (hf) with reduced ejection fraction (ef)
topic Cardiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8971068/
https://www.ncbi.nlm.nih.gov/pubmed/35371861
http://dx.doi.org/10.7759/cureus.22778
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