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Alkaline nucleoplasm facilitates contractile gene expression in the mammalian heart

Cardiac contractile strength is recognised as being highly pH-sensitive, but less is known about the influence of pH on cardiac gene expression, which may become relevant in response to changes in myocardial metabolism or vascularization during development or disease. We sought evidence for pH-respo...

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Detalles Bibliográficos
Autores principales: Hulikova, Alzbeta, Park, Kyung Chan, Loonat, Aminah A., Gunadasa-Rohling, Mala, Curtis, M. Kate, Chung, Yu Jin, Wilson, Abigail, Carr, Carolyn A., Trafford, Andrew W., Fournier, Marjorie, Moshnikova, Anna, Andreev, Oleg A., Reshetnyak, Yana K., Riley, Paul R., Smart, Nicola, Milne, Thomas A., Crump, Nicholas T., Swietach, Pawel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8971196/
https://www.ncbi.nlm.nih.gov/pubmed/35357563
http://dx.doi.org/10.1007/s00395-022-00924-9

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