Cargando…

Four novel candidate causal variants for deficient homozygous haplotypes in Holstein cattle

Mendelian variants can determine both insemination success and neonatal survival and thus influence fertility and rearing success of cattle. We present 24 deficient homozygous haplotype regions in the Holstein population of Switzerland and provide an overview of the previously identified haplotypes...

Descripción completa

Detalles Bibliográficos
Autores principales:	Häfliger, Irene M., Spengeler, Mirjam, Seefried, Franz R., Drögemüller, Cord
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8971413/ https://www.ncbi.nlm.nih.gov/pubmed/35361830 http://dx.doi.org/10.1038/s41598-022-09403-6

Ejemplares similares

Mining massive genomic data of two Swiss Braunvieh cattle populations reveals six novel candidate variants that impair reproductive success
por: Häfliger, Irene M., et al.
Publicado: (2021)

A major QTL at the LHCGR/FSHR locus for multiple birth in Holstein cattle
por: Widmer, Sarah, et al.
Publicado: (2021)

Associated regions for multiple birth in Brown Swiss and Original Braunvieh cattle on chromosomes 15 and 11
por: Widmer, Sarah, et al.
Publicado: (2022)

Reverse Genetic Screen for Deleterious Recessive Variants in the Local Simmental Cattle Population of Switzerland
por: Häfliger, Irene M., et al.
Publicado: (2021)

A homozygous missense variant in laminin subunit beta 1 as candidate causal mutation of hemifacial microsomia in Romagnola cattle
por: Jacinto, Joana G. P., et al.
Publicado: (2021)

A Missense Variant in PLP2 in Holstein Cattle with X-Linked Congenital Mast Cell Tumor
por: Jacinto, Joana G. P., et al.
Publicado: (2022)

An IL17RA frameshift variant in a Holstein cattle family with psoriasis-like skin alterations and immunodeficiency
por: Häfliger, Irene M., et al.
Publicado: (2020)

CNGB3 Missense Variant Causes Recessive Achromatopsia in Original Braunvieh Cattle
por: Häfliger, Irene M., et al.
Publicado: (2021)

A Heterozygous Missense Variant in the COL5A2 in Holstein Cattle Resembling the Classical Ehlers–Danlos Syndrome
por: Jacinto, Joana G. P., et al.
Publicado: (2020)

A de novo variant in the bovine ADAMTSL4 gene in an Original Braunvieh calf with congenital cataract
por: Häfliger, Irene M., et al.
Publicado: (2022)

A de novo start‐lost variant in ANKRD28 in a Holstein calf with dwarfism
por: Jacinto, Joana G. P., et al.
Publicado: (2022)

Candidate lethal haplotypes and causal mutations in Angus cattle
por: Hoff, Jesse L., et al.
Publicado: (2017)

A germline de novo variant in NUMB associated with a double‐outlet right ventricle in Chianina cattle
por: Jacinto, Joana G. P., et al.
Publicado: (2022)

High confidence copy number variants identified in Holstein dairy cattle from whole genome sequence and genotype array data
por: Butty, Adrien M., et al.
Publicado: (2020)

A De Novo Mutation in COL1A1 in a Holstein Calf with Osteogenesis Imperfecta Type II
por: Jacinto, Joana G. P., et al.
Publicado: (2021)

Clinicopathological Phenotype of Autosomal Recessive Cholesterol Deficiency in Holstein Cattle
por: Mock, T., et al.
Publicado: (2016)

A large deletion in the COL2A1 gene expands the spectrum of pathogenic variants causing bulldog calf syndrome in cattle
por: Jacinto, Joana Gonçalves Pontes, et al.
Publicado: (2020)

Homozygous haplotype deficiency reveals deleterious mutations compromising reproductive and rearing success in cattle
por: Pausch, Hubert, et al.
Publicado: (2015)

The impact of genetic relationship information on genomic breeding values in German Holstein cattle
por: Habier, David, et al.
Publicado: (2010)

A missense variant in DGKG as a recessive functional variant for hepatic fibrinogen storage disease in Wagyu cattle
por: Jacinto, Joana G. P., et al.
Publicado: (2023)

Lethal chondrodysplasia in a family of Holstein cattle is associated with a de novo splice site variant of COL2A1
por: Agerholm, Jørgen S., et al.
Publicado: (2016)

A de novo missense mutation of FGFR2 causes facial dysplasia syndrome in Holstein cattle
por: Agerholm, Jørgen S., et al.
Publicado: (2017)

A transposable element insertion in APOB causes cholesterol deficiency in Holstein cattle
por: Menzi, F., et al.
Publicado: (2016)

PRNP Haplotype Associated with Classical BSE Incidence in European Holstein Cattle
por: Murdoch, Brenda M., et al.
Publicado: (2010)

A frameshift insertion in FA2H causes a recessively inherited form of ichthyosis congenita in Chianina cattle
por: Jacinto, Joana G. P., et al.
Publicado: (2021)

X-Linked Hypohidrotic Ectodermal Dysplasia in Crossbred Beef Cattle Due to a Large Deletion in EDA
por: O’Toole, Donal, et al.
Publicado: (2021)

A Heterozygous Missense Variant in MAP2K2 in a Stillborn Romagnola Calf with Skeletal-Cardio-Enteric Dysplasia
por: Jacinto, Joana G. P., et al.
Publicado: (2021)

MOCOS‐associated renal syndrome in a Brown Swiss cattle
por: Jacinto, Joana G. P., et al.
Publicado: (2023)

GWAS Hits for Bilateral Convergent Strabismus with Exophthalmos in Holstein Cattle Using Imputed Sequence Level Genotypes
por: Bögeholz, Anke, et al.
Publicado: (2021)

Identification of two new recessive MC1R alleles in red‐coloured Evolèner cattle and other breeds
por: Hauser, Miriam, et al.
Publicado: (2022)

Novel Harmful Recessive Haplotypes Identified for Fertility Traits in Nordic Holstein Cattle
por: Sahana, Goutam, et al.
Publicado: (2013)

Confirmation of a non-synonymous SNP in PNPLA8 as a candidate causal mutation for Weaver syndrome in Brown Swiss cattle
por: Kunz, Elisabeth, et al.
Publicado: (2016)

Identification of factor XI deficiency in Holstein cattle in Turkey
por: Meydan, Hasan, et al.
Publicado: (2009)

Single nucleotide polymorphism and haplotype effects associated with somatic cell score in German Holstein cattle
por: Abdel-Shafy, Hamdy, et al.
Publicado: (2014)

Thrombocytopenic purpura on an organic farm with pen mating: a case report on the re-emergence of an old disease
por: Joller, Sara, et al.
Publicado: (2020)

Compound heterozygous PLA2G6 loss-of-function variants in Swaledale sheep with neuroaxonal dystrophy
por: Letko, Anna, et al.
Publicado: (2020)

DSP missense variant in a Scottish Highland calf with congenital ichthyosis, alopecia, acantholysis of the tongue and corneal defects
por: Häfliger, Irene M., et al.
Publicado: (2022)

A novel approach of homozygous haplotype sharing identifies candidate genes in autism spectrum disorder
por: Casey, Jillian P., et al.
Publicado: (2011)

Congenital nasolacrimal duct fistula in Brown Swiss cattle
por: Braun, Ueli, et al.
Publicado: (2014)

Causal relationships between milk quality and coagulation properties in Italian Holstein-Friesian dairy cattle
por: Tiezzi, Francesco, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_if2nb1kdoql7iaursv1ne94tdc