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Disease progression patterns and molecular resistance mechanisms to crizotinib of lung adenocarcinoma harboring ROS1 rearrangements
This retrospective study investigated the association between the pattern of disease progression and molecular mechanism of acquired resistance in a large cohort of 49 patients with ROS1-rearranged advanced non-small-cell lung cancer treated with first-line crizotinib. We found that treatment-emerge...
Autores principales: | Zhang, Yongchang, Huang, Zhe, Zeng, Liang, Zhang, Xiangyu, Li, Yizhi, Xu, Qinqin, Yang, Haiyan, Lizaso, Analyn, Xu, Chunwei, Liu, Jun, Wang, Wenxian, Song, Zhengbo, Ou, Sai-Hong Ignatius, Yang, Nong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8971474/ https://www.ncbi.nlm.nih.gov/pubmed/35361870 http://dx.doi.org/10.1038/s41698-022-00264-w |
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