Cargando…

Prognostic significance of AP-2α/γ targets as cancer therapeutics

Identifying genes with prognostic importance could improve cancer treatment. An increasing number of reports suggest the existence of successful strategies based on seemingly “untargetable” transcription factors. In addition to embryogenesis, AP-2 transcription factors are known to play crucial role...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kołat, Damian, Kałuzińska, Żaneta, Bednarek, Andrzej K., Płuciennik, Elżbieta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8971500/ https://www.ncbi.nlm.nih.gov/pubmed/35361846 http://dx.doi.org/10.1038/s41598-022-09494-1

Ejemplares similares

The biological characteristics of transcription factors AP-2α and AP-2γ and their importance in various types of cancers
por: Kołat, Damian, et al.
Publicado: (2019)

Functional genomics of AP-2α and AP-2γ in cancers: in silico study
por: Kołat, Damian, et al.
Publicado: (2020)

Determination of WWOX Function in Modulating Cellular Pathways Activated by AP-2α and AP-2γ Transcription Factors in Bladder Cancer
por: Kołat, Damian, et al.
Publicado: (2022)

WWOX Loses the Ability to Regulate Oncogenic AP-2γ and Synergizes with Tumor Suppressor AP-2α in High-Grade Bladder Cancer
por: Kołat, Damian, et al.
Publicado: (2021)

AP-2δ Is the Most Relevant Target of AP-2 Family-Focused Cancer Therapy and Affects Genome Organization
por: Kołat, Damian, et al.
Publicado: (2022)

In vitro and in silico assessment of the effect of WWOX expression on invasiveness pathways associated with AP-2 transcription factors in bladder cancer
por: Kałuzińska, Żaneta, et al.
Publicado: (2021)

Fragile Gene WWOX Guides TFAP2A/TFAP2C-Dependent Actions Against Tumor Progression in Grade II Bladder Cancer
por: Kołat, Damian, et al.
Publicado: (2021)

Corrigendum: Fragile Gene WWOX Guides TFAP2A/TFAP2C-Dependent Actions Against Tumor Progression in Grade II Bladder Cancer
por: Kołat, Damian, et al.
Publicado: (2021)

PLEK2, RRM2, GCSH: A Novel WWOX-Dependent Biomarker Triad of Glioblastoma at the Crossroads of Cytoskeleton Reorganization and Metabolism Alterations
por: Kałuzińska, Żaneta, et al.
Publicado: (2021)

Antineoplastic Nature of WWOX in Glioblastoma Is Mainly a Consequence of Reduced Cell Viability and Invasion
por: Kałuzińska-Kołat, Żaneta, et al.
Publicado: (2023)

Delineating the glioblastoma stemness by genes involved in cytoskeletal rearrangements and metabolic alterations
por: Kałuzińska-Kołat, Żaneta, et al.
Publicado: (2023)

Molecular landscapes of glioblastoma cell lines revealed a group of patients that do not benefit from WWOX tumor suppressor expression
por: Kałuzińska-Kołat, Żaneta, et al.
Publicado: (2023)

LINC01137/miR-186-5p/WWOX: a novel axis identified from WWOX-related RNA interactome in bladder cancer
por: Kołat, Damian, et al.
Publicado: (2023)

MicroRNAs: Their Role in Metastasis, Angiogenesis, and the Potential for Biomarker Utility in Bladder Carcinomas
por: Hammouz, Raneem Y., et al.
Publicado: (2021)

The artificial oxygen carrier erythrocruorin—characteristics and potential significance in medicine
por: Kruczkowska, Weronika, et al.
Publicado: (2023)

Exosomes as carriers transporting long non-coding RNAs: Molecular characteristics and their function in cancer
por: Kołat, Damian, et al.
Publicado: (2019)

Pyroptosis-related signatures in bladder cancer prognosis and treatment—are we there yet?
por: Kołat, Damian, et al.
Publicado: (2022)

Substances of Natural Origin in Medicine: Plants vs. Cancer
por: Gielecińska, Adrianna, et al.
Publicado: (2023)

PD-1/PD-L1 and DNA Damage Response in Cancer
por: Kciuk, Mateusz, et al.
Publicado: (2023)

Do selected lifestyle parameters affect the severity and symptoms of COVID-19 among elderly patients? The retrospective evaluation of individuals from the STOP-COVID registry of the PoLoCOV study
por: Kapusta, Joanna, et al.
Publicado: (2023)

Doxorubicin—An Agent with Multiple Mechanisms of Anticancer Activity
por: Kciuk, Mateusz, et al.
Publicado: (2023)

Long-COVID Clinical Features and Risk Factors: A Retrospective Analysis of Patients from the STOP-COVID Registry of the PoLoCOV Study
por: Chudzik, Michał, et al.
Publicado: (2022)

WWOX Tumor Suppressor Gene in Breast Cancer, a Historical Perspective and Future Directions
por: Pospiech, Karolina, et al.
Publicado: (2018)

Do COVID-19 Vaccinations Affect the Most Common Post-COVID Symptoms? Initial Data from the STOP-COVID Register–12-Month Follow-Up
por: Babicki, Mateusz, et al.
Publicado: (2023)

Do the Successive Waves of SARS-CoV-2, Vaccination Status and Place of Infection Influence the Clinical Picture and COVID-19 Severity among Patients with Persistent Clinical Symptoms? The Retrospective Study of Patients from the STOP-COVID Registry of the PoLoCOV-Study
por: Chudzik, Michał, et al.
Publicado: (2022)

Carboxymethyl Chitosan Hydrogels for Effective Wound Healing—An Animal Study
por: Kłosiński, Karol Kamil, et al.
Publicado: (2023)

Biocompatibility and Mechanical Properties of Carboxymethyl Chitosan Hydrogels
por: Kłosiński, Karol K., et al.
Publicado: (2022)

TGFα-EGFR pathway in breast carcinogenesis, association with WWOX expression and estrogen activation
por: Pospiech, Karolina, et al.
Publicado: (2022)

Basal keratin expression in breast cancer by quantification of mRNA and by immunohistochemistry
por: Kordek, Radzislaw, et al.
Publicado: (2010)

The WWOX/HIF1A Axis Downregulation Alters Glucose Metabolism and Predispose to Metabolic Disorders
por: Baryła, Izabela, et al.
Publicado: (2022)

Does vimentin help to delineate the so-called 'basal type breast cancer'?
por: Kusinska, Renata U, et al.
Publicado: (2009)

A Novel Set of WNT Pathway Effectors as a Predictive Marker of Uterine Corpus Endometrial Carcinoma–Study Based on Weighted Co-expression Matrices
por: Kośla, Katarzyna, et al.
Publicado: (2019)

Alternating expression levels of WWOX tumor suppressor and cancer-related genes in patients with bladder cancer
por: PŁUCIENNIK, ELŻBIETA, et al.
Publicado: (2014)

WWOX expression in colorectal cancer—a real-time quantitative RT-PCR study
por: Żelazowski, Maciej Jakub, et al.
Publicado: (2011)

The WWOX Gene Influences Cellular Pathways in the Neuronal Differentiation of Human Neural Progenitor Cells
por: Kośla, Katarzyna, et al.
Publicado: (2019)

Prognostic significance of lncRNA AP004608.1 in prostate cancer
por: Li, Wei, et al.
Publicado: (2022)

Molecular analysis of WWOX expression correlation with proliferation and apoptosis in glioblastoma multiforme
por: Kosla, Katarzyna, et al.
Publicado: (2010)

Whether and what abnormalities we find in ECG records and 24-hour Holter ECG in patients after COVID-19 without hospitalization with cardiac damage
por: Chudzik, M, et al.
Publicado: (2023)

Does the severity of the course of COVID-19 in pts without hospitalization and no history of cardiovascular disease affect of cardiac arrhythmias
por: Chudzik, M, et al.
Publicado: (2023)

The WWOX gene in brain development and pathology
por: Kośla, K, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_5mf180mm66ano44bnpuuflohdd