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The Role of Racial and Ethnic Factors in MicroRNA Expression and Risk for Type 2 Diabetes

Prior studies focused on circulating microRNAs and the risk for complex diseases have shown inconsistent findings. The majority of studies focused on European and East Asian racial or ethnic groups, however, ancestry was not typically reported. We evaluated the risk for type 2 diabetes as an exempla...

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Detalles Bibliográficos
Autores principales: Flowers, Elena, Kanaya, Alka M., Zhang, Li, Aouizerat, Bradley E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8971619/
https://www.ncbi.nlm.nih.gov/pubmed/35368704
http://dx.doi.org/10.3389/fgene.2022.853633
Descripción
Sumario:Prior studies focused on circulating microRNAs and the risk for complex diseases have shown inconsistent findings. The majority of studies focused on European and East Asian racial or ethnic groups, however, ancestry was not typically reported. We evaluated the risk for type 2 diabetes as an exemplar to show that race and ethnic group may contribute to inconsistent validation of previous findings of associations with microRNAs.