The Role of Racial and Ethnic Factors in MicroRNA Expression and Risk for Type 2 Diabetes

Prior studies focused on circulating microRNAs and the risk for complex diseases have shown inconsistent findings. The majority of studies focused on European and East Asian racial or ethnic groups, however, ancestry was not typically reported. We evaluated the risk for type 2 diabetes as an exempla...

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Detalles Bibliográficos
Autores principales: Flowers, Elena, Kanaya, Alka M., Zhang, Li, Aouizerat, Bradley E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8971619/
https://www.ncbi.nlm.nih.gov/pubmed/35368704
http://dx.doi.org/10.3389/fgene.2022.853633
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author Flowers, Elena
Kanaya, Alka M.
Zhang, Li
Aouizerat, Bradley E.
author_facet Flowers, Elena
Kanaya, Alka M.
Zhang, Li
Aouizerat, Bradley E.
author_sort Flowers, Elena
collection PubMed
description Prior studies focused on circulating microRNAs and the risk for complex diseases have shown inconsistent findings. The majority of studies focused on European and East Asian racial or ethnic groups, however, ancestry was not typically reported. We evaluated the risk for type 2 diabetes as an exemplar to show that race and ethnic group may contribute to inconsistent validation of previous findings of associations with microRNAs.
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spelling pubmed-89716192022-04-02 The Role of Racial and Ethnic Factors in MicroRNA Expression and Risk for Type 2 Diabetes Flowers, Elena Kanaya, Alka M. Zhang, Li Aouizerat, Bradley E. Front Genet Genetics Prior studies focused on circulating microRNAs and the risk for complex diseases have shown inconsistent findings. The majority of studies focused on European and East Asian racial or ethnic groups, however, ancestry was not typically reported. We evaluated the risk for type 2 diabetes as an exemplar to show that race and ethnic group may contribute to inconsistent validation of previous findings of associations with microRNAs. Frontiers Media S.A. 2022-03-18 /pmc/articles/PMC8971619/ /pubmed/35368704 http://dx.doi.org/10.3389/fgene.2022.853633 Text en Copyright © 2022 Flowers, Kanaya, Zhang and Aouizerat. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Genetics
Flowers, Elena
Kanaya, Alka M.
Zhang, Li
Aouizerat, Bradley E.
The Role of Racial and Ethnic Factors in MicroRNA Expression and Risk for Type 2 Diabetes
title The Role of Racial and Ethnic Factors in MicroRNA Expression and Risk for Type 2 Diabetes
title_full The Role of Racial and Ethnic Factors in MicroRNA Expression and Risk for Type 2 Diabetes
title_fullStr The Role of Racial and Ethnic Factors in MicroRNA Expression and Risk for Type 2 Diabetes
title_full_unstemmed The Role of Racial and Ethnic Factors in MicroRNA Expression and Risk for Type 2 Diabetes
title_short The Role of Racial and Ethnic Factors in MicroRNA Expression and Risk for Type 2 Diabetes
title_sort role of racial and ethnic factors in microrna expression and risk for type 2 diabetes
topic Genetics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8971619/
https://www.ncbi.nlm.nih.gov/pubmed/35368704
http://dx.doi.org/10.3389/fgene.2022.853633
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