Skeletal muscle-specific overexpression of miR-486 limits mammary tumor-induced skeletal muscle functional limitations

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miR-486 is a myogenic microRNA, and its reduced skeletal muscle expression is observed in muscular dystrophy. Transgenic overexpression of miR-486 using muscle creatine kinase promoter (MCK-miR-486) partially rescues muscular dystrophy phenotype. We had previously demonstrated reduced circulating an...

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Detalles Bibliográficos
Autores principales: Wang, Ruizhong, Kumar, Brijesh, Doud, Emma H., Mosley, Amber L., Alexander, Matthew S., Kunkel, Louis M., Nakshatri, Harikrishna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8971682/
https://www.ncbi.nlm.nih.gov/pubmed/35402076
http://dx.doi.org/10.1016/j.omtn.2022.03.009

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