Cargando…

Systemic Deficiency of PTEN Accelerates Breast Cancer Growth and Metastasis

Mutation or loss of the tumor suppressor gene PTEN or its functional status in tumor stromal cells may affect tumor occurrence, development, invasion, and metastasis, in which, however, the role of overall low PTEN expression, mutation, or deletion in the tumor-bearing host has rarely been reported....

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Jing, Sun, Jingjing, Wang, Qunfeng, Du, Yanze, Cheng, Jie, Yi, Juan, Xie, Bei, Jin, Suya, Chen, Gang, Wang, Lina, Wang, Xiaoyuan, Wei, Hulai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8971716/ https://www.ncbi.nlm.nih.gov/pubmed/35372075 http://dx.doi.org/10.3389/fonc.2022.825484

Ejemplares similares

Metformin and arsenic trioxide synergize to trigger Parkin/pink1-dependent mitophagic cell death in human cervical cancer HeLa cells
por: Chen, Jing, et al.
Publicado: (2021)

Tumor-infiltrating lymphocyte: features and prognosis of lymphocytes infiltration on colorectal cancer
por: Qin, Miao, et al.
Publicado: (2023)

New Treatment Opportunities in Phosphatase and Tensin Homolog (PTEN)-Deficient Tumors: Focus on PTEN/Focal Adhesion Kinase Pathway
por: Alfieri, Roberta, et al.
Publicado: (2017)

The m6A Methyltransferase METTL14-Mediated N6-Methyladenosine Modification of PTEN mRNA Inhibits Tumor Growth and Metastasis in Stomach Adenocarcinoma
por: Yao, Qi, et al.
Publicado: (2021)

PTEN loss promotes Warburg effect and prostate cancer cell growth by inducing FBP1 degradation
por: Song, Changze, et al.
Publicado: (2022)

Combined Anti-Cancer Effects of Platycodin D and Sorafenib on Androgen-Independent and PTEN-Deficient Prostate Cancer
por: Lu, Zongliang, et al.
Publicado: (2021)

Elevated Sodium Pump α3 Subunit Expression Promotes Colorectal Liver Metastasis via the p53-PTEN/IGFBP3-AKT-mTOR Axis
por: Wu, Di, et al.
Publicado: (2021)

Development and Validation of a Novel Model to Predict Regional Lymph Node Metastasis in Patients With Hepatocellular Carcinoma
por: Chen, Xiaoyuan, et al.
Publicado: (2022)

MicroRNA-1246 by Targeting AXIN2 and GSK-3β Overcomes Drug Resistance and Induces Apoptosis in Chemo-resistant Leukemia Cells
por: Xie, Bei, et al.
Publicado: (2021)

Relationship Between PTEN and Angiogenesis of Esophageal Squamous Cell Carcinoma and the Underlying Mechanism
por: Yang, Chenbo, et al.
Publicado: (2021)

Focus on PTEN Regulation
por: Bermúdez Brito, Miriam, et al.
Publicado: (2015)

Identification of Target PTEN-Based miR-425 and miR-576 as Potential Diagnostic and Immunotherapeutic Biomarkers of Colorectal Cancer With Liver Metastasis
por: Hu, Xiaoyun, et al.
Publicado: (2021)

TET1 inhibits gastric cancer growth and metastasis by PTEN demethylation and re-expression
por: Pei, Yao-fei, et al.
Publicado: (2016)

LncRNA SLCO4A1-AS1 Accelerates Growth and Metastasis of Gastric Cancer via Regulation of the miR-149/XIAP Axis
por: Fang, Yantian, et al.
Publicado: (2021)

Benzyl isothiocyanate suppresses development and metastasis of murine mammary carcinoma by regulating the Wnt/β-catenin pathway
por: Xie, Bei, et al.
Publicado: (2019)

Benzyl isothiocyanate suppresses development and metastasis of murine mammary carcinoma by regulating the Wnt/β-catenin pathway
por: Xie, Bei, et al.
Publicado: (2022)

Cooperative interactions of PTEN deficiency and RAS activation in melanoma metastasis
por: Nogueira, Cristina, et al.
Publicado: (2010)

MiR-454-3p Promotes Oxaliplatin Resistance by Targeting PTEN in Colorectal Cancer
por: Qian, Xiao-Lan, et al.
Publicado: (2021)

NK4 Regulates Laryngeal Squamous Cell Carcinoma Cell Properties and Inhibits Tumorigenicity by Modulating the DKK1/Wnt/β-Catenin Axis
por: Zhang, Shoukai, et al.
Publicado: (2021)

Case Report: Complete Response to Antiangiogenesis and Immune Checkpoint Blockade in an Unresectable MMR-Deficient Leiomyosarcoma Harboring Biallelic Loss of PTEN
por: Guo, Xi, et al.
Publicado: (2022)

Genomic Rearrangements of PTEN in Prostate Cancer
por: Phin, Sopheap, et al.
Publicado: (2013)

Platelet-promoting drug delivery efficiency for inhibition of tumor growth, metastasis, and recurrence
por: Li, Xiaoliang, et al.
Publicado: (2022)

ALDH1A3 Accelerates Pancreatic Cancer Metastasis by Promoting Glucose Metabolism
por: Nie, Shuang, et al.
Publicado: (2020)

Matrix Stiffness-Upregulated MicroRNA-17-5p Attenuates the Intervention Effects of Metformin on HCC Invasion and Metastasis by Targeting the PTEN/PI3K/Akt Pathway
por: Gao, Xiangyu, et al.
Publicado: (2020)

TRIM37 interacts with PTEN to promote the growth of human T-cell acute lymphocytic leukemia cells through regulating PI3K/AKT pathway
por: Qu, Honglan, et al.
Publicado: (2023)

ZKSCAN5 Activates VEGFC Expression by Recruiting SETD7 to Promote the Lymphangiogenesis, Tumour Growth, and Metastasis of Breast Cancer
por: Li, Jingtong, et al.
Publicado: (2022)

Loss of PTEN-Induced Kinase 1 Regulates Oncogenic Ras-Driven Tumor Growth By Inhibiting Mitochondrial Fission
por: Zhu, Dantong, et al.
Publicado: (2022)

Functions and Regulation of the PTEN Gene in Colorectal Cancer
por: Molinari, Francesca, et al.
Publicado: (2014)

PTEN: Multiple Functions in Human Malignant Tumors
por: Milella, Michele, et al.
Publicado: (2015)

The global change of gene expression pattern caused by PTEN mutation affects the prognosis of glioblastoma
por: Zhou, Shengjun, et al.
Publicado: (2022)

Machine Learning for the Prediction of Synchronous Organ-Specific Metastasis in Patients With Lung Cancer
por: Gao, Huan, et al.
Publicado: (2022)

Significance of PTEN Mutation in Cellular Process, Prognosis, and Drug Selection in Clear Cell Renal Cell Carcinoma
por: Fan, Caibin, et al.
Publicado: (2019)

Deficiency of Pten accelerates mammary oncogenesis in MMTV-Wnt-1 transgenic mice
por: Li, Yi, et al.
Publicado: (2001)

TSPAN7 Exerts Anti-Tumor Effects in Bladder Cancer Through the PTEN/PI3K/AKT Pathway
por: Yu, Xi, et al.
Publicado: (2021)

Case Report: Targeted Therapy for Metastatic Solid Pseudopapillary Neoplasm of the Pancreas With CTNNB1 and PTEN Mutations
por: Wang, Xinbo, et al.
Publicado: (2021)

Efficacy and safety of anti-epidermal growth factor receptor agents for the treatment of oesophageal cancer: a systematic review and meta-analysis
por: Zhang, Lijuan, et al.
Publicado: (2021)

Prediction of axillary lymph node metastasis in early breast cancer patients with ultrasonic videos based deep learning
por: Li, Wei-Bin, et al.
Publicado: (2023)

Identification of the Prognostic Signatures of Glioma With Different PTEN Status
por: Zhang, Pei, et al.
Publicado: (2021)

TP53-PTEN-NF1 depletion in human brain organoids produces a glioma phenotype in vitro
por: Singh, Sanjay K., et al.
Publicado: (2023)

Seminoma presenting as a solitary metastasis in gastric mucosa with regressed testicular mass
por: Yuan, Ren, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_sc3dtdt29mtci7nd0k2v71qcjk