Amiodarone Provides Long-Lasting Local Anesthesia and Analgesia in Open-State Mouse Nociceptors

Local anesthetics with long-lasting effects and selectivity for nociceptors have been sought over the past decades. In this study, we investigated whether amiodarone, a multiple channel blocker, provides long-lasting local anesthesia and whether adding a TRPV1 channel activator selectively prolongs...

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Detalles Bibliográficos
Autores principales: Kotoda, Masakazu, Matsuoka, Toru, Wada, Keiichi, Jayakar, Selwyn, Ino, Hirofumi, Kawago, Koji, Kumakura, Yasutomo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8971742/
https://www.ncbi.nlm.nih.gov/pubmed/35370742
http://dx.doi.org/10.3389/fphar.2022.872477

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