Targeting the tumor mutanome for personalized vaccination in a TMB low non-small cell lung cancer

BACKGROUND: Cancer is characterized by an accumulation of somatic mutations, of which a significant subset can generate cancer-specific neoepitopes that are recognized by autologous T cells. Such neoepitopes are emerging as important targets for cancer immunotherapy, including personalized cancer va...

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Detalles Bibliográficos
Autores principales: McCann, Katy, von Witzleben, Adrian, Thomas, Jaya, Wang, Chuan, Wood, Oliver, Singh, Divya, Boukas, Konstantinos, Bendjama, Kaidre, Silvestre, Nathalie, Nielsen, Finn Cilius, Thomas, Gareth, Sanchez-Elsner, Tilman, Greenbaum, Jason, Schoenberger, Stephen, Peters, Bjoern, Vijayanand, Pandurangan, Savelyeva, Natalia, Ottensmeier, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Clinical/Translational Cancer Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8971766/
https://www.ncbi.nlm.nih.gov/pubmed/35361728
http://dx.doi.org/10.1136/jitc-2021-003821

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8971766/
https://www.ncbi.nlm.nih.gov/pubmed/35361728
http://dx.doi.org/10.1136/jitc-2021-003821

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