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Ursolic acid improves the indoxyl sulfate-induced impairment of mitochondrial biogenesis in C2C12 cells

BACKGROUND/OBJECTIVES: Patients with chronic kidney disease (CKD) have a high concentration of uremic toxins in their blood and often experience muscle atrophy. Indoxyl sulfate (IS) is a uremic toxin produced by tryptophan metabolism. Although an elevated IS level may induce muscle dysfunction, the...

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Detalles Bibliográficos
Autores principales:	Sasaki, Yutaro, Kojima-Yuasa, Akiko, Tadano, Hinako, Mizuno, Ayaka, Kon, Atsushi, Norikura, Toshio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Nutrition Society and the Korean Society of Community Nutrition 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8971825/ https://www.ncbi.nlm.nih.gov/pubmed/35392531 http://dx.doi.org/10.4162/nrp.2022.16.2.147

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