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Sigma-1 receptor overexpression promotes proliferation and ameliorates cell apoptosis in β-cells

Sigma-1 receptor (Sig-1R) is a class of orphan receptors, the potential role of which in pancreatic islet cells remains poorly understood. The present study aimed to investigate the role of Sig-1R in islet β-cell proliferation and examine the effects of Sig-1R on islet β-cell injury under lipotoxic...

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Detalles Bibliográficos
Autores principales: Ke, Mengting, Lin, Fengping, Wang, Huawei, He, Guangzhen, Feng, Jieyuan, Song, Linyang, Xu, Yancheng, Liu, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8971912/
https://www.ncbi.nlm.nih.gov/pubmed/35302175
http://dx.doi.org/10.3892/mmr.2022.12686

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