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Enhancing epidemiological surveillance of the emergence of the SARS-CoV-2 Omicron variant using spike gene target failure data, England, 15 November to 31 December 2021

When SARS-CoV-2 Omicron emerged in 2021, S gene target failure enabled differentiation between Omicron and the dominant Delta variant. In England, where S gene target surveillance (SGTS) was already established, this led to rapid identification (within ca 3 days of sample collection) of possible Omi...

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Autores principales: Blomquist, Paula B, Bridgen, Jessica, Bray, Neil, O’Connell, Anne Marie, West, Daniel, Groves, Natalie, Gallagher, Eileen, Utsi, Lara, Jarvis, Christopher I, Hardstaff, Jo L, Byers, Chloe, Metelmann, Soeren, Simons, David, Zaidi, Asad, Twohig, Katherine A, Savagar, Bethan, Løchen, Alessandra, Ryan, Cian, Wrenn, Katie, Saavedra-Campos, María, Abedin, Zahidul, Florence, Isaac, Cleary, Paul, Elson, Richard, Vivancos, Roberto, Lake, Iain R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8971917/
https://www.ncbi.nlm.nih.gov/pubmed/35301981
http://dx.doi.org/10.2807/1560-7917.ES.2022.27.11.2200143
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author Blomquist, Paula B
Bridgen, Jessica
Bray, Neil
O’Connell, Anne Marie
West, Daniel
Groves, Natalie
Gallagher, Eileen
Utsi, Lara
Jarvis, Christopher I
Hardstaff, Jo L
Byers, Chloe
Metelmann, Soeren
Simons, David
Zaidi, Asad
Twohig, Katherine A
Savagar, Bethan
Løchen, Alessandra
Ryan, Cian
Wrenn, Katie
Saavedra-Campos, María
Abedin, Zahidul
Florence, Isaac
Cleary, Paul
Elson, Richard
Vivancos, Roberto
Lake, Iain R
author_facet Blomquist, Paula B
Bridgen, Jessica
Bray, Neil
O’Connell, Anne Marie
West, Daniel
Groves, Natalie
Gallagher, Eileen
Utsi, Lara
Jarvis, Christopher I
Hardstaff, Jo L
Byers, Chloe
Metelmann, Soeren
Simons, David
Zaidi, Asad
Twohig, Katherine A
Savagar, Bethan
Løchen, Alessandra
Ryan, Cian
Wrenn, Katie
Saavedra-Campos, María
Abedin, Zahidul
Florence, Isaac
Cleary, Paul
Elson, Richard
Vivancos, Roberto
Lake, Iain R
author_sort Blomquist, Paula B
collection PubMed
description When SARS-CoV-2 Omicron emerged in 2021, S gene target failure enabled differentiation between Omicron and the dominant Delta variant. In England, where S gene target surveillance (SGTS) was already established, this led to rapid identification (within ca 3 days of sample collection) of possible Omicron cases, alongside real-time surveillance and modelling of Omicron growth. SGTS was key to public health action (including case identification and incident management), and we share applied insights on how and when to use SGTS.
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spelling pubmed-89719172022-04-13 Enhancing epidemiological surveillance of the emergence of the SARS-CoV-2 Omicron variant using spike gene target failure data, England, 15 November to 31 December 2021 Blomquist, Paula B Bridgen, Jessica Bray, Neil O’Connell, Anne Marie West, Daniel Groves, Natalie Gallagher, Eileen Utsi, Lara Jarvis, Christopher I Hardstaff, Jo L Byers, Chloe Metelmann, Soeren Simons, David Zaidi, Asad Twohig, Katherine A Savagar, Bethan Løchen, Alessandra Ryan, Cian Wrenn, Katie Saavedra-Campos, María Abedin, Zahidul Florence, Isaac Cleary, Paul Elson, Richard Vivancos, Roberto Lake, Iain R Euro Surveill Rapid Communication When SARS-CoV-2 Omicron emerged in 2021, S gene target failure enabled differentiation between Omicron and the dominant Delta variant. In England, where S gene target surveillance (SGTS) was already established, this led to rapid identification (within ca 3 days of sample collection) of possible Omicron cases, alongside real-time surveillance and modelling of Omicron growth. SGTS was key to public health action (including case identification and incident management), and we share applied insights on how and when to use SGTS. European Centre for Disease Prevention and Control (ECDC) 2022-03-17 /pmc/articles/PMC8971917/ /pubmed/35301981 http://dx.doi.org/10.2807/1560-7917.ES.2022.27.11.2200143 Text en This article is copyright of the authors or their affiliated institutions, 2022. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.
spellingShingle Rapid Communication
Blomquist, Paula B
Bridgen, Jessica
Bray, Neil
O’Connell, Anne Marie
West, Daniel
Groves, Natalie
Gallagher, Eileen
Utsi, Lara
Jarvis, Christopher I
Hardstaff, Jo L
Byers, Chloe
Metelmann, Soeren
Simons, David
Zaidi, Asad
Twohig, Katherine A
Savagar, Bethan
Løchen, Alessandra
Ryan, Cian
Wrenn, Katie
Saavedra-Campos, María
Abedin, Zahidul
Florence, Isaac
Cleary, Paul
Elson, Richard
Vivancos, Roberto
Lake, Iain R
Enhancing epidemiological surveillance of the emergence of the SARS-CoV-2 Omicron variant using spike gene target failure data, England, 15 November to 31 December 2021
title Enhancing epidemiological surveillance of the emergence of the SARS-CoV-2 Omicron variant using spike gene target failure data, England, 15 November to 31 December 2021
title_full Enhancing epidemiological surveillance of the emergence of the SARS-CoV-2 Omicron variant using spike gene target failure data, England, 15 November to 31 December 2021
title_fullStr Enhancing epidemiological surveillance of the emergence of the SARS-CoV-2 Omicron variant using spike gene target failure data, England, 15 November to 31 December 2021
title_full_unstemmed Enhancing epidemiological surveillance of the emergence of the SARS-CoV-2 Omicron variant using spike gene target failure data, England, 15 November to 31 December 2021
title_short Enhancing epidemiological surveillance of the emergence of the SARS-CoV-2 Omicron variant using spike gene target failure data, England, 15 November to 31 December 2021
title_sort enhancing epidemiological surveillance of the emergence of the sars-cov-2 omicron variant using spike gene target failure data, england, 15 november to 31 december 2021
topic Rapid Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8971917/
https://www.ncbi.nlm.nih.gov/pubmed/35301981
http://dx.doi.org/10.2807/1560-7917.ES.2022.27.11.2200143
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